摘要
采用解吸电晕束电离源（DCBI）与质谱联用法测定食品包装材料中的双酚A。优化了萃取溶剂和离子源等参数。DCBI优化后，甲醇为萃取溶剂，检测模式为负离子模式，电离电压为-2kV，离子传输管温度225℃，He气体流速1．0L/min。当选用全扫描的模式时，单个样品测定时间小于30s，对双酚A的检出限为0．1mg／L，在1—100mg／L浓度范围内线性良好，相关系数达到0．98，直接检测食品包装材料中的双酚A时，平均回收率为94％～125％，测定结果的相对标准偏差（RSD）小于17％。本方法分析速度快，灵敏度高，基体影响小，适用于大量样品快速检测。
A novel method, based on desorption corona beam ionization （DCBI） tandem mass spectrometry （MS）, was developed for the direct detection of bisphenol A in food packaging materials with minimal sample pretreatment. We optimized DCBI-MS conditions （i. e. extraction solvent and ionization source ） using representative bisphenol A standards. The reagent solvent was methanol at high voltage （-2.0 kV, negative ion detection mode）. The temperature of the heated capillary was optimized to be 225 ℃. The flow rate of He was 1.0 L/min. The limit of detection （LOD） of these amino acids was 〈 0.1 mg/L, and the linear dynamic range was 1-100 mg/L. The bisphenol A concentration in food packaging material samples was measured by the method, and the average time for a single sample analysis was less than 30 s. The recovery rates for different concentrations ranged from 94% to 125%, and the relative standard deviation （RSD） was less than 17%. This study showed that DCBI-MS was a powerful tool for the rapid, sensitive, and quantitative detection of bisphenol A amino acids in complex meterials samples.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2014年第1期88-92,共5页
Chinese Journal of Analytical Chemistry
基金
国家自然科学基金项目(Nos.21177025
21377028)资助~~
关键词
解吸电晕束电离源
双酚A
包装材料
单重四级杆质谱
Desorption corona beam ionization
Bisphenol A
Packaging materials
Single quadrupole
