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乳腺癌干性表型癌细胞的临床意义 被引量：3

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摘要 乳腺癌是女性最常见的恶性肿瘤，病死率居全球首位。近20年，由于早期发现和辅助治疗的改进，乳腺癌的治疗疗效已明显提升，但很多患者仍面临复发的恐惧和死亡的威胁。现阶段，乳腺癌总体复发率约40％，其中60％～70％的患者发生远处转移。应用常规化疗药物联合治疗，HER-2阳性早期转移性乳腺癌对trastuzumab的反应率为50％-84％，但疗程开始1年内药物即对患者失效。
作者 张众 谢丰培 Gary Guishan Xiao
机构地区 大连医科大学病理学教研室 Creighton University Medical Center
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2014年第1期1-5,共5页 Chinese Journal of Clinical and Experimental Pathology
关键词 乳腺肿瘤 干性表型 靶基因
分类号 R737.9 [医药卫生—肿瘤]
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参考文献22

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同被引文献19

  • 1Minal Garg.Epithelial-mesenchymal transition- activating transcription factors- multifunctional regulators in cancer[J].World Journal of Stem Cells,2013,5(4):188-195. 被引量：28
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临床与实验病理学杂志
2014年 第1期

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