摘要
目的 总结原位肝移植术后上消化道出血的常见原因及其处理问题。方法 回顾性总结了 48例原位肝移植术后 3例上消化道出血的临床资料 ,分析了其可能原因 ,处理及对肝移植的影响。结果 本组 3例上消化道出血 ,均发生在术后 2个月内。出血前发生过急性排斥反应或感染等。 2例伴有胆道出血 ,经介入治疗后出血停止。 2例死于再次溃疡大出血 ,1例痊愈。结论 溃疡出血是肝移植术后上消化道大出血的常见原因 ,多次出血者预后不良。
Objective To investigate the causes and treatment of upper gastrointestinal bleeding(UGIB)after orthotopic liver transplantation.Methods Data of 3 cases with UGIB from 48 patients with orthotopic liver transplantation was retrospectively reviewed.The bleeding causes, impact on patient and graft survival were analyzed.Results 3 of 48 patients were identified who had at least one bleeding episode from a gastrontestinal source.All three patients developed acute rejection or sepsis before the UGIB occurred during the first postoperative two monthes.Hemobilia was found in 2 of 3 UGIB patients and the bleeding was halted after therapeutic intervention.2 of 3 patients died of de novo UGIB from ulcers,one was cured after interventional procedures and conservative management.Conclusion Ulcers are the most common causes of UGIB following orthotopic liver transplantation.Repeateol bleeding episodes appear to be particularly ominous.
出处
《肝胆外科杂志》
2000年第6期424-426,共3页
Journal of Hepatobiliary Surgery
关键词
原位肝移植
上消化道出血
介入治疗
Orthotopic liver transplantation Upper gastrontestinal bleeding Interventional procedure
