摘要
目的应用三维斑点追踪(3D-STI)技术评价阻塞型睡眠呼吸暂停低通气综合征(OSAHS)伴高血压(HT)患者左心室整体收缩功能。方法 OSAHS 40例,分为单纯OSAHS组20例和OSAHS+HT组20例;另选择20名健康正常人作为正常对照组。行常规超声心动图检查,采集左心室心尖四腔三维全容积图像,存储图像并应用3D-STI分析软件在线分析,计算左心室整体纵向收缩峰值应变(GLS)、左心室整体径向收缩峰值应变(GRS)、左心室整体圆周收缩峰值应变(GCS)及左心室整体面积收缩峰值应变(GAS)。结果与正常对照组相比,OSAHS组左心室GLS、GRS、GAS减低(P均<0.05),OSAHS+HT组左心室GLS、GRS、GCS、GAS均减低(P均<0.05)。与OSAHS组比较,OSAHS+HT组左心室GLS、GCS、GAS均减低(P均<0.05)。结论 OSAHS合并HT患者存在左心室收缩功能受损。3D-STI能早期、准确有效地评估其左心室整体收缩功能改变。OSAHS患者心脏结构及功能变化独立于HT而单独存在,二者同时存在时改变加重。
Objective To evaluate the left ventricular (LV) global systolic function with three-dimensional speckle track- ing echocardiography (3D-STI) in obstructive sleep apnea hypopnea syndrome (OSAHS) patients with hypertension (HT). Methods Totally 40 patients with OSAHS were divided into simple OSAHS group (n=20) and OSAHS with HT group (n=20). In addition, 20 healthy people were set as the control group. All subjects were examined with echocar- diography to obtain 3D apical four-chamber images. 3D-STI software was applied to acquire the LV global longitudinal peak systolic strain (GLS), global radial peak systolic strain (GRS), global circumferential peak systolic strain (GCS) and glob- al area peak systolic strain (GAS). Results Compared with control group, LV GLS, GRS, GAS reduced in OSAHS group (P^0.05), while GLS, GRS, GCS and GAS reduced in OSAHS with HT group (P〈0.05). Compared with those in OS- AHS group, GLS, GCS, GAS were lower in OSAHS with HT group (P^0.05). Conclusion 3D-STI can identify early functional LV changes in OSAHS patients with HT. Changes of cardiac structure and function of OSAHS patients are in- dependent of the presence of HT, though HT aggravates the structure and function abnormalities of LV in patients with OSAHS.
出处
《中国医学影像技术》
CSCD
北大核心
2014年第1期53-57,共5页
Chinese Journal of Medical Imaging Technology
关键词
超声心动描记术
三维斑点追踪技术
睡眠呼吸暂停
阻塞性
高血压
心室功能
左
Echoeardiography
Three-dimensional speckle tracking
Sleep apnea, obstructive
Hypertension
Ventricu-lar function, left