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三维斑点追踪技术评价阻塞型睡眠呼吸暂停低通气综合征伴高血压患者左心室整体收缩功能 被引量:4

Three-dimensional speckle tracking echocardiography in evaluation on left ventricular global systolic function in obstructive sleep apnea hypopnea syndrome patients with hypertension
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摘要 目的应用三维斑点追踪(3D-STI)技术评价阻塞型睡眠呼吸暂停低通气综合征(OSAHS)伴高血压(HT)患者左心室整体收缩功能。方法 OSAHS 40例,分为单纯OSAHS组20例和OSAHS+HT组20例;另选择20名健康正常人作为正常对照组。行常规超声心动图检查,采集左心室心尖四腔三维全容积图像,存储图像并应用3D-STI分析软件在线分析,计算左心室整体纵向收缩峰值应变(GLS)、左心室整体径向收缩峰值应变(GRS)、左心室整体圆周收缩峰值应变(GCS)及左心室整体面积收缩峰值应变(GAS)。结果与正常对照组相比,OSAHS组左心室GLS、GRS、GAS减低(P均<0.05),OSAHS+HT组左心室GLS、GRS、GCS、GAS均减低(P均<0.05)。与OSAHS组比较,OSAHS+HT组左心室GLS、GCS、GAS均减低(P均<0.05)。结论 OSAHS合并HT患者存在左心室收缩功能受损。3D-STI能早期、准确有效地评估其左心室整体收缩功能改变。OSAHS患者心脏结构及功能变化独立于HT而单独存在,二者同时存在时改变加重。 Objective To evaluate the left ventricular (LV) global systolic function with three-dimensional speckle track- ing echocardiography (3D-STI) in obstructive sleep apnea hypopnea syndrome (OSAHS) patients with hypertension (HT). Methods Totally 40 patients with OSAHS were divided into simple OSAHS group (n=20) and OSAHS with HT group (n=20). In addition, 20 healthy people were set as the control group. All subjects were examined with echocar- diography to obtain 3D apical four-chamber images. 3D-STI software was applied to acquire the LV global longitudinal peak systolic strain (GLS), global radial peak systolic strain (GRS), global circumferential peak systolic strain (GCS) and glob- al area peak systolic strain (GAS). Results Compared with control group, LV GLS, GRS, GAS reduced in OSAHS group (P^0.05), while GLS, GRS, GCS and GAS reduced in OSAHS with HT group (P〈0.05). Compared with those in OS- AHS group, GLS, GCS, GAS were lower in OSAHS with HT group (P^0.05). Conclusion 3D-STI can identify early functional LV changes in OSAHS patients with HT. Changes of cardiac structure and function of OSAHS patients are in- dependent of the presence of HT, though HT aggravates the structure and function abnormalities of LV in patients with OSAHS.
出处 《中国医学影像技术》 CSCD 北大核心 2014年第1期53-57,共5页 Chinese Journal of Medical Imaging Technology
关键词 超声心动描记术 三维斑点追踪技术 睡眠呼吸暂停 阻塞性 高血压 心室功能 Echoeardiography Three-dimensional speckle tracking Sleep apnea, obstructive Hypertension Ventricu-lar function, left
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