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2型糖尿病患者颈动脉粥样硬化斑块相关危险因素分析 被引量:7

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摘要 目的:研究2型糖尿病(T2DM)颈动脉粥样硬化斑块患者的相关危险因素。方法:对238例住院的T2DM患者行双侧颈动脉彩色B超检查,根据颈动脉内中膜厚度(IMT)及颈动脉有无斑块,分为非斑块组(颈动脉IMT<1.5mm和无颈动脉斑块)、斑块组(颈动脉IMT≥1.5mm和颈动脉斑块),记录相关临床资料并测定生化指标及踝臂指数(ABI)。结果:两组高血压病史、年龄、T2DM病程、收缩压(SBP)、低密度脂蛋白—胆固醇(LDL-C)、空腹血糖(FBG)、糖化血红蛋白(HbAlc)、同型半胱氨酸(Hcy)、ABI差异有统计学意义(P<0.01或P<0.05)。颈动脉粥样硬化斑块与ABI呈负相关,与高血压病史、年龄、T2DM病程、SBP、LDL-C、Hcy、HbAlc呈正相关。Logistic回归分析表明高血压病史、年龄、SBP、LDL-C、Hcy、HbAlc、ABI是T2DM患者颈动脉粥样硬化斑块的独立危险因素。结论:高血压病史、SBP、年龄、LDL-C、Hcy、HbAlc、ABI可能参与了T2DM合并颈动脉粥样硬化斑块的形成,ABI可作为动脉粥样硬化斑块的一个简便可靠的预测因子。
出处 《广西医科大学学报》 CAS 2013年第6期914-916,共3页 Journal of Guangxi Medical University
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