摘要
目的探讨临床治疗过程中采用来氟米特联合贝那普利治疗慢性肾小球肾炎的具体疗效情况,为后期肾小球治疗工作提供参考性意见。方法选取我院2009年3月—2011年3月收治慢性肾小球肾炎患者132例,将患者随机分为治疗组(66例)和对照组(66例),两组均口服贝那普利进行治疗,治疗组患者在此基础上采用来氟米特联合治疗,对两组患者的总体治疗效果情况进行分析。结果治疗组总有效率为87.9%,高于对照组的75.7%,差异有统计学意义(P<0.05)。结论采用来氟米特联合贝那普利能够起到降低尿蛋白含量的效果,其疗效以及安全性是值得肯定的。
Objective To discuss the effect of treating chronic glomerulonephritis with leflunomide combined with benazepril to provide envidence in future work. Methods 132 chronic glomerulonephritis patients were divided into study group and controlled group with 66 cases in each other. All these groups were treated with benazepril, and study group were treated with leflunomide. Compared the total effect of these two groups. Results The total effetive rate of study group was 87. 9%, higher than 75.7% in controlled group. Conclusion Treating hronic glomerulonephritis with leflunomide combined benazepril can decrease urine protein content with less adverse effects to extend in clinic.
出处
《临床合理用药杂志》
2013年第36期42-42,44,共2页
Chinese Journal of Clinical Rational Drug Use