摘要
目的分析医院西药房处方不合理应用情况,提高用药安全性。方法回顾性分析医院2012年西药房12 874份处方,分析不合理类型和科室分布。结果12 874份处方中共有296份处方不合理,占2.30%。处方不合理应用情况主要为给药剂量和用药疗程不合理,分别占30.74%和25.00%。以妇产科、儿科和老年科最常见,分别为3.31%,3.00%和2.55%。抗菌药物处方不合理率为3.93%,其中最常见的为配伍禁忌和选药错误,分别占39.19%和22.97%。不合理应用处方中不良反应发生率为66.22%,合理应用处方不良反应发生率为3.67%(P<0.05),其中以皮肤损害最常见,占46.94%。结论西药房处方不合理情况依然存在,应加强处方审核、监督,保证用药安全。
Objective To analyze the irrational application situation of prescriptions in the pharmacy,in order to increase the safety of medication. Methods 12 874 pieces of prescription in the pharmacy during 2012 were analyzed retrospectively. The types of irrational application and the distribution of departments were investigated. Results Among 12 874 pieces of prescription,296 pieces of irrational prescription were found, which accounted for 2.30%. The medicine dose and the course of treatment were the main irrational types, which accounted for 30. 74% and 25.00% , respectively. The irrational rates were the highest in the departments of gynecology and ob- stetrics,pediatrics and geriatrics,which accounted for 3.31%,3.00% and 2.55%,respectively. The irrational rate of antimicrobial pre- scription was 3.93% ,of which the most common types were the incompatibility of drugs and the error of drug selection of drug-use, accounting for 39.19% and 22. 97% , respectively. The incidence rate of adverse reactions in the iirational and rational antimicrobial prescriptions were 66. 22% and 3.67% respectively,the difference between them showing statistical significance （P 〈 0. 05）,in which the skin damage was the most common, accounting for 46. 94%. Conclusion The unreasonable situation of prescriptions still exists in our hospital pharmacy. The prescription audit and supervision should be strengthened to ensure the safety of medication.
出处
《中国药业》
CAS
2013年第24期47-48,共2页
China Pharmaceuticals
关键词
处方
安全用药
西药房
药学服务
prescriptions
safety of medication
pharmacy
pharmaceutical service
