摘要
全球约1/3人群感染丙型肝炎病毒(HCV)。HCV感染是慢性肝炎、肝硬化和肝衰竭的主要病因之一,慢性丙型肝炎的有效治疗方法在全球均是紧迫的医疗难题之一。相当多的慢性丙型肝炎患者,特别是基因1、4型HCV感染者、原发无应答者、
出处
《现代医药卫生》
2013年第24期3722-3726,共5页
Journal of Modern Medicine & Health
参考文献35
-
1Cernescu C, Ruta S, Gheorghe L, et al. The flying publisher guide to hepatitis C treatment[M/OL]. Bemd Kamps Steinh~iuser Verlag 2011 : 58-7812013-08-01].http ://scripts.sil.org/OFL.
-
2Gonzalez SA, Keeffe EB. Management of chronic hepatitis C treat- ment failures : role of consensus interferon[J]. Biologics, 2009,3 : 141-150.
-
3Sjogren MH, Sjogren R, Hohzmuller K, et al. Interferon alfacon-1 and ribavirin versus interferon alpha-2b and ribavirin in the treat- ment of chronic hepatitis C[J]. Dig Dis Sci, 2005,50 (4) : 727-732.
-
4Leevy CB. Consensus interferon and ribavirin in patients with chronic hepatitis C who were nonresponders to pegylated inter- feron alfa-2b and ribavirin[J]. Dig Dis Sci ,2008,53 (7):1961- 1966.
-
5Bacon BR, Shiffman ML, Mendes F, et al. Retreating chronic he- patitis C with daily interferon alfacon-1/ribavirin after nonresponse to pegylated interferon/ribavirin : DIRECT results[J]. Hepatology, 2009,49(6) : 1838-1846.
-
6Meyer DF,Tobias H, Min AD, et al. Retreatment of patients non-responsive to pegylated interferon and ribavirin with daily high- dose consensus interferon[J]. Hepat Res Treat, 2010,2010: 537827.
-
7Kishida Y, Imaizumi N, Tanimura H, et al. Restoration of innate and adaptive immune responses by HCV viral inhibition with an induction approach using natural interferon-beta in chronic hep- atitis C[J]. Clin Dev Immunol, 2012,2012 : 582716.
-
8Arase Y, Suzuki Y, Suzuki F, et al. Efficacy of reduction therapy of natural human ~-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 2 and high virus load[J]. He- patol Res, 2012,42(8) :750-756.
-
9Arase Y ,Kawamura Y ,Suzuki Y ,et al. Efficacy of reduction therapy of natural human 13-interferon and ribavirin in elderly patients with chronic hepatitis C ,genotype lb and high viral load[J]. He- patol Res,2012,42(10) :949-957.
-
10Couzigou P, P6msat S, Bourli~re M, et al. Interferon-gamma with peginterferon alpha-2a and ribavirin in nonresponder patientsI / with chronic hepatitis C (ANRS HC16 GAMMATRI)[J]. J Gast / troenterol Hepatol, 2013,28 (2) : 329-334. |.
同被引文献44
-
1Andrew Lee,Jeremy Rajanayagam,Mona Abdel-Hady.Chronic Hepatitis C Infection in Children: Current Treatment and New Therapies[J].Journal of Clinical and Translational Hepatology,2015,3(1):36-41. 被引量:2
-
2Mortada Hassan El-Shabrawi,Naglaa Mohamed Kamal Alanani.Burden of pediatric hepatitis C[J].World Journal of Gastroenterology,2013,19(44):7880-7888. 被引量:11
-
3中华医学会肝病学分会,中华医学会感染病学分会.慢性乙型肝炎防治指南[S].2005-12-10.
-
4姜娟.干扰素的用药教育与用药实践分析[C].2013年中国临床药学学术年会暨第九届临床药师论坛论文集.2013.
-
5陈红.聚乙二醇化重组集成干扰素在丙型肝炎受试者中耐受性和早期疗效分析[D].长春:吉林大学,2013.
-
6Marcelo S,Jorge P,Cutler D,et al. A randomised trial to compare the pharmacokinetic, pharmacodynamic, and antiviral effects of peginterferon alfa - 2b in patients with chronic hepatitis C [J]. J Hepatol, 2006,45 : 204-213.
-
7Jenny H,Bressler B,Wang B,et al. Pharmakokinetics and response of obese patients with chronic hepatitis C treat- ed with different doses of PEG - IFNot 2a (40KD) (Pe- gasys) [J]. Br J Clin Pharmacol,2009,67:280-287.
-
8Danish F A, Koul S S, Subhani F R, et al. Antiviral therapy in HCV-infected decompensated cirrhotics [ J 1.SaudiJGastroenterol,2010,16(4):310-314.
-
9魏来主编.丙型肝炎临床诊断及治疗[M].北京:科学出版社,2012:77.
-
10Janicko M, Veseltny E, Lesko D, et al. Serum cholester- ol is a significant and independent mortality predictor in liver cirrhosis patients [ J ]. Ann Hepatol, 2013,12 ( 4 ) : 581-587.
引证文献4
-
1毕京峰,刘佳,周渝霞,周芃,朱真珍,王敏,段锋,魏振满.聚乙二醇α-2a干扰素在健康人体中的药代动力学研究[J].中国医药导报,2014,11(34):93-96.
-
2王志超,杜豪伟,栗朋辉.乙型肝炎患者血清免疫球蛋白的临床检验分析[J].临床医药文献电子杂志,2015,2(24):4991-4991. 被引量:5
-
3熊锦华,曹建彪,李绍祥,陈力强,范公忍.失代偿期丙型肝炎肝硬化脾栓塞术后聚乙二醇干扰素联合利巴韦林抗病毒治疗效果观察[J].解放军医药杂志,2015,27(9):77-81. 被引量:6
-
4喻增建,金生.小儿丙型肝炎抗病毒治疗进展[J].现代医药卫生,2016,32(24):3816-3818. 被引量:1
二级引证文献12
-
1李彩.免疫球蛋白水平对乙肝患者的临床意义[J].中国卫生检验杂志,2016,26(12):1747-1748. 被引量:11
-
2蒿自睿.聚乙二醇干扰素α-2a治疗慢性丙型肝炎对甲状腺功能及甲状腺相关抗体影响临床研究[J].现代诊断与治疗,2016,27(9):1666-1667. 被引量:1
-
3刘爱芳.小剂量干扰素联合利巴韦林治疗丙型肝炎失代偿期肝硬化的疗效观察[J].临床医药文献电子杂志,2016,3(18):3699-3700. 被引量:1
-
4季华.小剂量聚乙二醇干扰素α-2a 联合利巴韦林抗病毒治疗失代偿期丙型肝炎肝硬化的疗效[J].中国实用医刊,2016,43(22):33-35. 被引量:2
-
5朴红心.慢性丙型肝炎特殊人群的抗病毒治疗[J].现代医药卫生,2017,33(20):3076-3079.
-
6闫忠.乙型肝炎患者血清免疫球蛋白临床检验结果分析[J].黑龙江医药,2017,30(6):1369-1370. 被引量:9
-
7唐萍.血清免疫球蛋白、总胆红素、凝血酶原活动度联合检测在诊治慢性乙型肝炎中的应用价值[J].当代医药论丛,2018,16(10):4-6. 被引量:10
-
8邓文华.布拉氏酵母菌治疗小儿腹泻对细胞免疫功能的影响[J].中国现代药物应用,2018,12(14):138-139. 被引量:5
-
9姚路静.复方丹参片辅助胸腺法新治疗32例失代偿期丙肝肝硬化的效果及预后分析[J].医学理论与实践,2018,31(18):2739-2741.
-
10陈国胜,胡立芬,许夕海,李家斌.新型布尼亚病毒感染致发热伴血小板减少综合征临床特点及预后影响指标[J].中国医学装备,2017,14(5):94-97. 被引量:14
-
1王虹,许颂霄,尹一兵.荧光定量PCR检测HCV-RNA的研究进展[J].国际检验医学杂志,2006,27(1):74-76. 被引量:3
-
2喻增建,金生.小儿丙型肝炎抗病毒治疗进展[J].现代医药卫生,2016,32(24):3816-3818. 被引量:1
-
3吴剑华.正确认识保肝药物的地位和临床应用(一) 保肝治疗的必要性[J].中国社区医师,2010,26(40):9-9.
-
4蔡宝祥,应永秋.抗病毒新药奥司他韦的研究进展[J].安徽医药,2006,10(7):533-535. 被引量:5
-
5周泉,李艳,童永清,汪明,徐万洲.武汉地区丙型肝炎病毒基因分型与慢性丙型肝炎患者肝功能和血液指标分析[J].国际检验医学杂志,2013,34(13):1693-1695. 被引量:9
-
6王新宇,尹有宽,张继明.聚乙二醇干扰素治疗丙型肝炎的新进展[J].中国新药与临床杂志,2004,23(2):116-119. 被引量:5
-
7贺永文,刘薇,曾令兰,熊开均,罗端德.Effect of interferon in combination with ribavirin on the plus and minus strands of HCV RNA in patients with chronic hepatitis C[J].World Journal of Gastroenterology,1996,2(3):179-181.
-
8涂业桃,张筱惠,邓剑.丙型肝炎患者血清自身抗体检测的相关分析[J].现代医药卫生,2015,31(23):3546-3548. 被引量:4
-
9王敏,乐晓华,韩红星,蒋小玲,陆坚.HCV-RNA病毒载量和肝脏病理的关系[J].实用医学杂志,2006,22(13):1513-1514. 被引量:10
-
10陈暖,张俏忻,程碧珍.提高丙型肝炎诊断准确性的检测方法[J].中国校医,2015,29(6):431-431. 被引量:1