摘要
The role of Fas/Fas ligand (FasL) in mediating alveolar macrophage (AM)-derived inflammatory cytokines in 29 human lung silicosis patients and 6 controls was studied. It showed that the serum levels of IL-1β, TNF-a, IL-8, MIP-la, MCP-1, and TGF-β1 were higher in silicosis patients than in controls, and increased with the progression of silicosis except TGF-β1 and IL-8. TGF-β1, IL-8, MCP-1,
The role of Fas/Fas ligand (FasL) in mediating alveolar macrophage (AM)-derived inflammatory cytokines in 29 human lung silicosis patients and 6 controls was studied. It showed that the serum levels of IL-1β, TNF-a, IL-8, MIP-la, MCP-1, and TGF-β1 were higher in silicosis patients than in controls, and increased with the progression of silicosis except TGF-β1 and IL-8. TGF-β1, IL-8, MCP-1,
基金
supported by the Natural Science Foundation of China (30671741)
the Pneumoconiosis Treatment Foundation for China Coal Miners (2005-03)
the Science and Technology Support Program of Hebei Province (09276196D)