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Role of Fas/FasL Pathway-mediated Alveolar Macrophages Releasing Inflammatory Cytokines in Human Silicosis 被引量:14

Role of Fas/FasL Pathway-mediated Alveolar Macrophages Releasing Inflammatory Cytokines in Human Silicosis
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摘要 The role of Fas/Fas ligand (FasL) in mediating alveolar macrophage (AM)-derived inflammatory cytokines in 29 human lung silicosis patients and 6 controls was studied. It showed that the serum levels of IL-1β, TNF-a, IL-8, MIP-la, MCP-1, and TGF-β1 were higher in silicosis patients than in controls, and increased with the progression of silicosis except TGF-β1 and IL-8. TGF-β1, IL-8, MCP-1, The role of Fas/Fas ligand (FasL) in mediating alveolar macrophage (AM)-derived inflammatory cytokines in 29 human lung silicosis patients and 6 controls was studied. It showed that the serum levels of IL-1β, TNF-a, IL-8, MIP-la, MCP-1, and TGF-β1 were higher in silicosis patients than in controls, and increased with the progression of silicosis except TGF-β1 and IL-8. TGF-β1, IL-8, MCP-1,
出处 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2013年第11期930-933,共4页 生物医学与环境科学(英文版)
基金 supported by the Natural Science Foundation of China (30671741) the Pneumoconiosis Treatment Foundation for China Coal Miners (2005-03) the Science and Technology Support Program of Hebei Province (09276196D)
关键词 FASL AM
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