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急性白血病患者血清sHLA-G水平测定的临床意义

Clinical significance of serum levels of sHLA-G in patients with acute leukemia
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摘要 目的:探讨血清sHLA-G在急性白血病中的临床意义。方法:采用双抗体夹心酶联免疫吸附法(ELISA)检测124例急性白血病患者血清中sHLA-G水平。结果:急性白血病初诊患者血清sHLA-G水平明显高于正常对照组(P<0.05),完全缓解期sHLA-G水平恢复正常,未缓解和复发患者sHLA-G水平与初诊患者无明显差异(P>0.05)。结论:sHLA-G表达水平变化可能与急性白血病的病情发展、疗效及预后有关。 Objective： To investigate clinical significance of sHLA - G in patients with acute leukemia. Methods ： Serum levels of sHLA - G in 124 patients with acute leukemia were determined by enzyme - linked immunosorbent assay（ELISA）. Results：The serum level of sHLA - G in initial patient with acute leukemia was significantly higher than that of control group （P 〈 0.05 ）, and decreased to normal in patients at complete remission period. There was no difference in sHLA -G between nonremission and relapse and initial patients（ P 〉 0.05 ）. Conclusion：Serum level of sHLA - G might influence the treatment outcomes and can serve as a prognostic factor for acute leukemia.
作者 宋斌 章正华 陈雁 万楚成
机构地区 湖北医药学院附属太和医院血液内科
出处 《现代肿瘤医学》 CAS 2013年第12期2801-2803,共3页 Journal of Modern Oncology
关键词 白血病 急性 sHLA—G leukemia acute sHLA - G
分类号 R733.71 [医药卫生—肿瘤]
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参考文献11

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现代肿瘤医学
2013年 第12期

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