摘要
目的 :回顾性分析维持性血液透析 (CHD)患者的人口统计学和流行病学特点。 方法 :从 1974年 1月至 1999年 4月 ,在南京军区南京总医院肾脏病研究所血液净化中心接受CHD治疗的患者 2 0 0 4例 ,分析了患者的性别、年龄、原发病因、治疗持续时间和转归 ,及 1995年以后CHD患者的死亡原因。 结果 :2 0 0 4例尿毒症患者中以中、青年为主 ,平均年龄 41 7± 13 5岁 ,男 /女为 2 2∶1,其中 38 5 %患者原发病因不明 ,已知病因者以原发性肾小球肾炎为主 ,占 6 6 1% ,经肾活检明确诊断者以IgA肾病最多见 ;继发性肾小球疾病占 17 1% ,其中狼疮性肾炎占首位 ,糖尿病和高血压病居其次 ,分别占 6 1%、4 9%和 2 1% ;777例CHD患者在本中心治疗时间超过 3个月 ,其中18 4%仍在我院HD治疗 ,最长者已存活 16年 ;31 9%患者行肾移植 ,30 4%转至外院治疗 ,3 90 %改为腹膜透析 ,13 9%患者死亡 ;近年来患者的主要死因为脑血管意外 (36 7% )和急性左心衰 (2 0 0 % )。CHD患者 1年生存率93 2 % ,5年生存率 6 4 2 % ,10年生存率 5 5 1%。 结论 :①本组患者以中、青年为主 ,男性多见 ;②IgA肾病是导致尿毒症的主要已知病因 ;③CHD患者 1年、5年和 10年生存率分别为 93 2 %、6 4 2 %和 5 5 1% 。
To ana lyze the demographic and epidemiologic data of hemodialyze patients during the last 25 years in the Blood Purification Cen ter of Research Institute of Nephrology, Jinling Hospital. METHODOLOG Y This is a retrospective an alysis which included 2004 maintained he modialysis patients treated between Janu ary 1974 and April 1999.Data on the demo graphic and epidemiologic aspects of the se patients were examined,life expectanc y and gross mortality rate were calculat ed. RESULTS In t his group of patients,the average age at start of hemodialysis was 41.7±13.5 ,with 71.1% between the age of 20 and 50 .In the analysis of the diseases causing ESRD,primary glomerulonephritis account ed for 66.1%,secondary glomerular diseas e for 17.1%,chronic tubulo-interstitial nephritis for 9.7%,hereditary-congenital disease for 4.6% and other causes for 2 .4%.In primary glomerulonephritis,IgA Ne phropathy was the most common type.And i n secondary glomerulonephritis,lupus nep hritis,diabetic nephropathy and hyperten sive nephrosclerosis were the top three common types.In the maintenance hemodial ysis patients with long term follow-up i n the center (n=777),31.9% of them received renal transplantation,30.4% transferred to other hospitals for hemodialysis,and 13.9% died.The most frequent causes of d e ath in maintenance hemodialysis patients were cerebral vascular disease and hear t failure in recent years.The 1-year,5-ye ar and 10-year survival rate of chronic hemodialysis patients was 93.2%,64.2% an d 55.1% respectively,and the gross morta lity rate(GMR)of 1-and 5-year was 10.2% and 4.1%. CON CLUSION In this center,most of the patients at start of hemodial ysis were in the age of 20～50,with prima ry glomerular disease as the most common cause for ESRD.In maintenance hemodial ysis patients,the survival rates of 1-ye a r,5-year and 10-year were 93.2%,64.2% an d 55.1% respectively.The most frequent ca uses of death in this group of patients were cerebral and heart vascular diseases.
出处
《肾脏病与透析肾移植杂志》
CAS
CSCD
2000年第5期405-410,共6页
Chinese Journal of Nephrology,Dialysis & Transplantation
关键词
血液透析
生存率
流行病学
maintenance hemodialysis
survival rate
epidemiology
