摘要
为了解麻疹疫苗 (MV)强化免疫的效果 ,福建省 1999年在进行MV强化免疫活动中 ,随机抽取 30 5名儿童检测血清ELISA-IgG抗体。结果显示 :在强化免疫前有 78 37%的儿童处于易感和低抗体水平。通过强化免疫 ,人群抗体阳性率由免疫前的6 8 2 0 %升至免疫后的 97 38% ,几何平均滴度 (GMT)由 1:96 99升至 1:175 1 6 6。免疫前处于易感的儿童抗体阳转率达91 75 %。说明强化免疫对控制麻疹暴发 ,进一步消除麻疹起到十分重要的作用。建议对 1～
In order to evaluate the efficacy of supplementary immunization of measles vaccine in Fujian Province in 1999, 305 vaccinated children were chosen randomly, and their serum samples were tested for measles IgG with ELISA. The results showed as follows. The children whose antibody level before immunization were undetected or under low level accounted for 78.37%. Positive seroconversion rate rose from 68.20% to 97.38% and GMT rose from 1:96.99 to 1:1,751 66 by supplementary immunization. Positive seroconversion rate was 91.75%in children who were measles IgG negative before supplementary immunization. Supplementary immunization had played an important role in controlling measles outbreak and eliminating measles. Authors suggest that we should go on vaccinating 1～14 year old children who has not been listed as the targets of supplementary immunization.
出处
《中国计划免疫》
2000年第6期358-360,共3页
Chinese Journal of Vaccines and Immunization
关键词
麻疹疫苗
强化免疫
血清学研究
Measles vaccine
Supplementary immunization
Serological survey
