摘要
目的 :研究正常人和高血压患者不同部位动脉缓冲功能的变化。方法 :对 12 0例正常人和 2 0 5例原发性高血压患者应用动脉搏波速度 (PulsewavevelocityPWV)测定仪进行检测。颈动脉 -股动脉PWV(CFPWV)、肱动脉 -挠动脉PWV(BRPWV)和股动脉 足背动脉PWV(FTPWV)分别为反映大动脉和中等动脉扩张性 (Distensibility)的参数 ,并能敏感反映动脉缓冲功能的改变。结果 :无论正常人还是高血压患者 ,CFPWV与年龄和收缩压成正相关关系 (P均小于 0 0 0 1) ,而BRPWV和FTPWV并不随年龄和收缩压的改变而改变。结论 :正常人和高血压患者不同部位动脉节段的缓冲功能发生不同的变化 ,大动脉扩张性降低 ,中等动脉无明显变化。对大动脉缓冲功能变化的早期检测和有效治疗具有重要的临床价值。
Objective:To determine artery buffering function at different artery segments in normotensive subjects and patients with essential hypertension. Methods:Automatic pulse wave velocity(PWV) measurement was applied to examine 120 normotensive subjects and 205 hypertensive patients. Carotid\|femoral PWV(CFPWV) and brachial\|radial PWV(BRPWV) and femoral\|tibial PWV(FTPWV) were the parameters reflecting large arterial and middle\|sized arterial distensibility. Results:Carotid\|femoral PWV was positively related to age and systolic blood pressure(both \%P\%<0 001), while brachial\|radial PWV and femoral\|tibial PWV were not changed with age and systolic blood pressure in both normotensive subjects and hypertensive patients. Conclusion:Buffering function among different arterial segments would have different change during hypertension. Distensibility of large artery was reduced, but middle\|sized artery had no significant change. To early examine change of large artery buffering function and to apply effective therapy have important clinical value in essential hypertension.
出处
《高血压杂志》
CSCD
2000年第4期292-294,共3页
Chinese Journal of Hypertension
关键词
高血压
动脉
扩张性
脉搏波速度
hypertension
artery
distensibility
pulse wave velocity
