摘要
目的 :探讨大剂量葛根素对心绞痛治疗的可行性。方法 :87例患者随机分为 2组 ,治疗组 42例 ,对照组 45例。治疗组应用葛根素注射液 12 0 0 m g加入 5 %葡萄糖 5 0 0 ml静滴 ,对照组用硝酸甘油 5 m g加入 5 %葡萄糖 2 5 0 ml静滴 ,比较 2组疗效。结果 :治疗组在减少心绞痛发作次数、显效率、总有效率、心电图缺血性 ST段恢复及心肌耗氧量减少等指标上 ,与对照组比较无显著差异 (P均 >0 .0 5 )。结论 :大剂量葛根素有改善心肌缺血、缓解冠状动脉痉挛等作用 。
Objective:To investigate the feasibility of treating acutely severe angina pectoris(AP) with large dose puerarin.Methods:Eightyseven patients were randomly divided into two groups,treated group ( n =42) and control group ( n =45).The treated group was treated with puerarin injection 1 200 mg+5% glucose 500 ml infused intravenously but control group was treated with nitroglycerine 5 mg+5% glucose 250 ml infused intravenously.Results:In respect of reducing attack times of AP,markedly effective rate,total effective rate,recovering ischemic ST segment of electrocardiogram,decreasing volume of oxygen consumption,there were not markedly differents between the two groups (all P >0 05).Conclusions:Large dose of puerarin possesses the effects on improving myocardial ischemia and blood viscosity,remitting spasm of coronary artery so that its curative effects on AP is obvious.
出处
《中国中西医结合急救杂志》
CAS
2000年第6期368-269,共1页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词
心绞痛
葛根素
硝酸甘油
中医药疗法
angina pectoris
puerarin
large dosage
nitroglycerine
traditional Chinese medicine
