摘要
冠心病的炎症学说逐渐得到大家认可。许多基础和临床研究证实超敏C反应蛋白(high-sensitivity C-reactive protein,hs-CRP)不仅是炎症的非特异性标志物,本身亦直接参与心血管疾病的病理过程。hs-CRP对于冠心病的诊断和治疗具有重要指导意义,尤其是可以作为健康人冠心病风险的有效预测因子。本文综述hs-CRP与冠心病的关系及致病机制的研究进展。
The inflammation theory for coronary heart disease is gradually recognized. Many basic and clinical studies confirmed that the high-sensitivity C-reactive protein （hs-CRP） is not only a non-specific marker for inflammation, but it also directly involves in the pathological process of cardiovascular diseases. It plays a significant role in guiding the diagnosis and treatment of coronary heart disease, especially in predicting the risk for coronary heart disease in healthy people. The relation between the hs-CRP and coronary heart disease, as well as pathogenic mechanism ofhs-CRP in coronary heart disease is reviewed in this article.
出处
《国际病理科学与临床杂志》
CAS
2013年第5期437-441,共5页
Journal of International Pathology and Clinical Medicine
基金
四川省教育厅重点项目(08zc061)~~
关键词
超敏C反应蛋白
冠心病
标志物
high-sensitivity C-reactive protein
coronary heart disease
biomarker
