摘要
目的分析特异性治疗慢性咳嗽的疗效及对患者细胞免疫的影响。方法对50例慢性咳嗽患者根据基础病因进行特异性治疗,观察治疗前后的疗效,检测治疗前后患者外周血CD3+、CD4+、CD8+水平。结果治疗4周后显效29例(58.00%),有效17例(34.00%),无效4例(8.00%)。与治疗前比较,治疗4周后50例患者CD3+、CD4+水平及CD4/CD8比值显著提高,CD8+显著降低,差异均有统计学意义(P<0.05)。结论针对慢性咳嗽患者基础病因的特异性治疗可促进患者气道炎症消除,改善机体免疫功能,提高疗效。
Objective To understand the effects of ' specificity treatment' on chronic cough and lymphocytes immune function. Method 50 patients with chronic cough were selected as subjects of study and given ' specificity treatment' . The levels of CD3 + , CD4 + , CD8 + were measured and compared before and after the treatment was implemented. The effects of the treatment was then observed treatment effects. Findings 4 weeks after the treatment was implemented, 29 of the 50 patients were found to have been cured(58.00% ), disease symptom in 17 of the 50 cases(34.00% ) were found to have effectively reduced, and no effects were observed in 4 cases (8.00%) ; CD3 + , CD4 + levels and CD4 +/CD8 + ratio were higher than before treatment ( P 〈 0. 05 ) ; CD8 + was lower than before treatment ( P 〈 0. 05 ). Conclusion ' Specificity treatment' can effectively eliminate airway inflammation, improve lymphocytes immune function, and enhance efficacy of treatment.
出处
《健康研究》
CAS
2013年第5期358-360,共3页
Health Research
关键词
慢性咳嗽
特异性治疗
T细胞免疫
疗效
chronic cough
specific treatment
T cell immunity
c]inical effects