摘要
目的研究神经节苷脂联合纳洛酮治疗新生儿缺氧缺血性脑病的临床疗效。方法选取2011年3月。2013年3月我院新生儿缺氧缺血性脑病患者120例，经医学伦理委员会通过，患者知情同意随机分为研究组和对照组，每组60例，两组患儿均采用常规治疗，对照组在此基础上加用纳洛酮进行治疗，研究组在对照组的基础上加用神经节苷脂进行治疗，治疗时间均为12d，比较两组的临床疗效以及神经行为评分。结果研究组总有效率明显高于对照组总有效率，治疗6d后和12d后，研究组神经行为评分明显高于对照组神经行为评分，两组比较差异有统计学意义（P〈0．05）。结论神经节苷脂联合纳洛酮治疗新生儿缺氧缺血性脑病具有良好的临床疗效，可以明显的改善患JWN功能。
Objective To study the ganglioside naloxone combination treatment of neonatal hypoxic-ischemic encephalopathy clinical efficacy. Methods March 2011 to March 2013 in our hospital neonatal hypoxic-ischemic encephalopathy 120 patients by the medical ethics committee passed informed consent of patiems were randomly divided into study group and control group 60 cases, two group of children were using conventional treatment,the control group -was based on the use of naloxone treatment, the study group were based on the use of ganglioside treatment, treatment time was 12 days,compared two groups clinical and neurobehavioral score. Results The study group was significantly higher total efficiency,6 days and 12 days after treatment,the study group was significantly higher behavioral neurological neurobehavioral scores, the two groups were statistically significant （P 〈 0.05）. Conclusion The combined naloxone ganglioside treatment of neonatal hypoxic-ischemic encephalopathy with good clinical efficacy,can significantly improve brain function in children.
出处
《中国医药科学》
2013年第20期55-56,共2页
China Medicine And Pharmacy
