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慢性腹膜透析和血液透析患者的血脂改变 被引量:9

Lipid profiles of patients with continuous ambulatory peritoneal dialysis and maintenance hemodialysis
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摘要 目的 :了解连续性不卧床腹膜透析 (CAPD)和维持性血液透析 (MHD)患者血脂水平改变。 方法 :对上海市 12家单位 10 5例 CAPD和 199例 MHD患者血脂水平进行横断面调查。 结果 :CAPD和 MHD患者血 TG和 apo B均显著增高 ,血HDL- ch、HDL2 、apo A1和 L CAT均显著低于正常 ,以上指标在血、腹透组之间无显著差异。CAPD组血浆 L p(a)水平显著高于正常组和 MHD组。 结论 :CAPD和 MHD患者脂质代谢紊乱相当常见 ,以前者更为突出。 Objective: To investigate the blood lipid profile of CAPD and MHD patients. Methods: A cross sectional study was conducted on blood lipids of CAPD and MHD patients in 12 hospitals in Shanghai, and the results were compared with those of 50 normal controls. Results: Compared with normal controls, blood TG and apoB increased while HDL ch, HDL 2, apoA1/apoB and LCAT activity decreased significantly in CAPD and MHD patients. There was no difference between the 2 groups concerning the above lipid parameters. CAPD patients also had increased blood TC, LDL ch and Lp(a). Conclusion: Hyperlipidemia is quite common in dialysis patients, which seems to be more severe in CAPD patients. [
出处 《第二军医大学学报》 CAS CSCD 北大核心 2000年第11期1026-1028,共3页 Academic Journal of Second Military Medical University
基金 国家自然科学基金资助项目 ( 3 92 70 3 4 5 )
关键词 腹膜透析 血液透析 脂质代谢 血脂 peritoneal dialysis hemodialysis lipid metabolism
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