摘要
重症急性胰腺炎(SAP)是公认的危重难治性疾病。病死率高达36%~50%。近年来,中西医结合治疗重症急性胰腺(SAP)取得了显著进展,但一些制约疗效进一步提高的难点成为当前关注的热点问题。其主要体现在中西医结合治疗SAP的确切疗效未确立和治疗方案的不统一,对SAP病情的评估和严重程度的预测尚无简便易行的指标,一些新技术和具有争议的治疗方法尚缺乏高质量的循证医学证据,中医药治疗SAP的机制尚未阐明。因此,现阶段从事中西医结合治疗SAP的方向应是中西医有机结合,加强多学科合作,统一认识,推行中医药临床路径;继续深入研究早期评估和预测病情严重程度的指标,提高诊疗水平;联合开展基础和临床方面研究,探明中医药治疗治疗SAP的机制,寻找最佳的治疗方案,改善预后。
Severe acute pancreatitis (SAP) is recognized as critical refractory disease. The case fatality rate of SAP is as high as 36% -50%. Although significant progress has been achieved on the treatment of severe acute pancreatitis (SAP) by Integrated Traditional Chinese Medicine (TCM) and Western Medicine (WM), there still exist some difficulties hindering the further improvement of therapeutic efficacy. The hot issues includes: unconfirmative curative effects and diverse treatment principles, complicated predictive scoring systems and inaccurate markers for the severity stratification, unproved new therapeutic tools and controversial methods waiting more high qualified evidence, unclarified mechanism of Integrated TCM and WM. In order to overcome the difficulties, we aim to launch the clinical pathway of Integrated TCM and WM, to strengthen the unity of multidisciplinary cooperation. We also need to keep the efforts on screening the markers for early evaluation and prediction of disease severity, improving the diagnosis and treatment, exploring the mechanism of Traditional Chinese Medicine in treating SAP with more high quality basic and clinical research. Based on these efforts, we could provide better treatments and prognosis for SAP patients.
出处
《四川大学学报(医学版)》
CAS
CSCD
北大核心
2013年第6期962-965,共4页
Journal of Sichuan University(Medical Sciences)
关键词
重症急性胰腺炎
中西医结合治疗
热点
Severe acute pancreatitis Treatment of Integrated Traditional Chinese and WesternMedicine Hot issue