期刊文献+

碘131与抗甲状腺药物治疗甲亢疗效对比 被引量:8

Comparison of Curative Effect of I 131 and Antithyroid Drugs for Hyperthyroidism
原文传递
导出
摘要 目的:探讨碘131和抗甲状腺药物治疗甲状腺功能亢进的疗效。方法:选择2009年5月~2013年5月间于我院就诊的甲状腺功能亢进患者为研究对象,按照治疗方法的不同分为治疗组和对照组,治疗组的患者接受碘131治疗,对照组患者采用抗甲状腺药物治疗。观察治疗1年后2组患者的有效率和复发情况。结果:治疗1年后,治疗组的有效率为92.86%,观察组的有效率为65.85%,差异有统计学意义(P〈0.05)。治疗组的复发率为2.38%,观察组的复发率为19.51%,差异有统计学意义(P〈0.05)。结论:碘131是一种治疗甲状腺功能亢进的安全可靠、疗效明显的方法,可以在临床上推广使用,但其远期疗效仍需进一步的探讨。 Objective :To explore the curative effect of I131 and antithyroid drugs for hyperthyroidism. Methods:The patients of hy- perthyroidism visiting in the endocrinology department of our hospital from May 2009 to May 2012 were taken as the study objects. The patients were grouped into case and control. The case group was treated with I 131, and the control group were treated with antithyroid drugs. The observation indexes were effective rate and recurrence rate of the patients. Results:The effective rate of case group was 92. 86%, the effective rate of control group was 65.85%, the difference was statistically significant( P 〈 0.05). The recurrence rate of case group was 2.38%, the recurrence rate of control group was 19.51%, the difference was statistically significant ( P 〈 0.05 ). Conclusion: I131 was a safe, reliable and effective treatment for hyperthyroidism, can be generalized and used in clinical practice.
出处 《中国伤残医学》 2013年第11期33-34,共2页 Chinese Journal of Trauma and Disability Medicine
关键词 碘131 抗甲状腺药物 甲状腺功能亢进 疗效 I131, Antithyroid drugs, Hyperthyroidism, Curative effect
  • 相关文献

参考文献4

二级参考文献13

  • 1曹慧玲,鹿洁,刘敏,王善菊.TPOAb检测对自身免疫性甲状腺病诊治的价值[J].放射免疫学杂志,2004,17(3):203-204. 被引量:14
  • 2Walter MA, Christ-Crain M, Eckard B, et al. Radioiodine therapy in hyperthyroidism: inverse correlation of pretherapeutic iodine uptake level and post-therapeutic outcome [ J ]. Eur J Clin Invest, 2004, 34 (5) : 365 -370.
  • 3Listewnik MH. Analysis of factors affecting treatment results for toxic goiter with radioactive ^131 I[ J]. Ann Acad Med Stetin, 2000, 46(2) : 109 - 121.
  • 4Larsen PR, Davies TF, Hay ID. The thyroid gland. In: Wilson JD. Foster DW, Kronenberg HM, eds. Williams textbook of endocrinology. 9th ed[M]. Philadelphia: WB sauaders,1998,447-448.
  • 5Korber C, Schneider P, Korber-Hafner N, et al. Antithyroid drugs as a factor influencing the outcome of Radioiodine therapy in Graves and toxic nodular goitre[J]. Eur J Nucl Med, 2001,28:1360-1364.
  • 6Veliz J, Pineda G, Arancibia P, et al. Treatment of diffuse hyperthyroid goiter with radioiodine influence of prophylthiouracil pretreatment (ab)[J].Rev Medicine, 2000,128(6):609-612.
  • 7李少林.核医学[M].第1版,北京:人民卫生出版社,2002.
  • 8Esfahani AF, Kakhki VR, Fallahi B,et al. Comparative evaluation of two fixed doses of 185 and 370MBq ^131I, for the treatment of Graves' disease resistant to antithyroid drugs[J]. Hell J Nucl Med,2005,Sep- Dec; 8(3):158-161.
  • 9Schneider P, Korber C, Korber-Hafner N,et al. Does an individual estimation of half-life improve the results of radioiodine therapy of Graves' disease[J].Nuklearmedizin. 2002 Dec; 41(6):240-244.
  • 10邢家骝.^131I治疗甲状腺疾病[M].北京:人民卫生出版社,2002:223-224.

共引文献32

同被引文献44

引证文献8

二级引证文献33

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部