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泌尿系恶性肿瘤中长链非编码RNA表达变化的研究进展 被引量：1

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摘要 长链非编码RNA（lncRNA）是一类长度介于200 nt～ 100 kb之间的RNA,位于细胞核和细胞质中,在真核细胞中普遍被转录[1].IncRNA具有mRNA样结构,经过剪切,具有polyA尾巴和启动子结构,但序列中缺少开放阅读框（ORF）,而不具有或很少有编码蛋白质的功能.通过先进的全基因组技术分析真核生物的转录过程,发现大多数的人类基因组转录会产生大量的长链非编码RNA,并将它的位置定位到内含子或基因之间的区域[2].
作者 宫再兴 王共先 刘伟鹏 郝鹏
机构地区 南昌大学第一附属医院
出处 《山东医药》 CAS 2013年第38期96-99,共4页 Shandong Medical Journal
关键词 长链非编码RNA 泌尿系肿瘤 前列腺癌抗原
分类号 R737.1 [医药卫生—肿瘤]
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参考文献36

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二级参考文献11

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  • 10谢小娟,李旭,王帆,陈葳.非编码RNAUCA1基因的细胞定位和组织表达谱分析[J].南方医科大学学报,2010,30(1):57-60. 被引量：38

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山东医药
2013年 第38期

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