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右美托咪定术中镇静研究进展 被引量:12

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摘要 术中镇静可有效抑制患者的不良应激反应,减少血流动力学波动,使患者在手术及各项操作中更为舒适.理想的镇静药物应具备的条件:镇静效果确切,起效快,对循环及呼吸系统功能影响小,镇静深度易于控制,半衰期短,代谢产物无毒性,不良反应最少.但目前尚无药物完全满足上述条件.以往常用咪达唑仑、丙泊酚等药物对患者进行术中镇静,但均有不同程度的呼吸抑制,且血流动力学波动较大.右美托咪定为高效和高选择性的α2肾上腺素能受体激动剂,具有镇静、催眠、抗焦虑、镇痛、抑制交感神经等作用,而无呼吸抑制作用,不良反应少而轻.现将局部麻醉、椎管内麻醉、监护麻醉及全身麻醉下,右美托咪定在各种手术及操作中的应用综述如下.
出处 《中国药物与临床》 CAS 2013年第11期1439-1441,共3页 Chinese Remedies & Clinics
基金 广东省科技计划项目(2012B031800417)
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参考文献26

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二级参考文献39

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