摘要
目的探讨睡眠呼吸暂停低通气综合征(SAHS)患者QT离散度(QTd)变化及心律失常的发生情况。方法选取2011年12月—2012年12月因疑有睡眠通气障碍而在我院使用多导睡眠仪(PSG)进行睡眠监测并同步行动态心电图监测的患者132例,对患者进行整夜(>7 h)PSG监测,同步检查动态心电图。根据睡眠呼吸暂停低通气指数(AHI),将患者分为SAHS组与非SAHS组,比较两组QTd变化及心律失常的发生情况。结果 SAHS组QTd、校正QT离散度(QTcd)、QTpeak离散度(QTpd)均高于非SAHS组(P<0.05)。SAHS组患者发生心律失常40例(40.8%),高于非SAHS组的8例(23.5%)(χ2=4.606,P<0.05)。QTd与QTcd、QTd与QTpd、QTcd与QTpd均呈正相关(r值分别为0.799、0.690和0.705,P<0.05)。结论 SAHS患者QTd增大、心律失常发生率增高,QTd增大可能提示SAHS患者夜间发生心脏性猝死风险增加。
Objective To investigate the variations of QT dispersion （QTd） and the incidence rate of cardiac arrhythmia in sleep apnea hypopnea syndrome （SAHS） patients. Methods From December 2011 to December 2012, 132 suspected cases of SAHS received both overnight （ 〉7 h） sleep monitoring using polysomnography （PSG） and Holter monitor electrocardiography. According to the apnea - hypopnea index （ AHI）, the patients were divided into the SAHS group and the non - SAHS group. The variations of QTd and the incidence rate of cardiac arrhythmia were compared between the two groups. Results The QTd, QTcd and QTpd in the SAHS group were significantly higher than those in the non - SAHS group （ P 〈 0. 05 ） . The inci- dence rate of cardiac arrhythmia in the SAHS group [ 40 cases （40. 8% ） ] was significantly higher than that （8 cases （23.5%） in the non - SAHS group （X^2 = 4. 606, P 〈 0. 05 ） . A certain positive correlation exited between QTd and QTcd, QTd and QTpd, QTcd and QTpd, respectively （ r values were 0. 799, 0. 690 and 0. 705, respectively, P 〈 0.05 ） . Conclusion The incidence rate of cardiac arrhythmia and QTd in SAHS patients increased, the increased QTd may indicate an increased risk of sudden cardiac death （SCD） at night.
出处
《中国全科医学》
CAS
CSCD
北大核心
2013年第30期3551-3553,共3页
Chinese General Practice
基金
苏州市科技发展计划项目(SYS201237)
