摘要
HD-Zip转录因子属于Homeobox蛋白家族,是植物特异转录因子,由高度保守的HD(Homeodomain)结构域和Leu zipper(Zip)元件组成,前者与DNA特异结合,后者介导蛋白二聚体的形成。HD-Zip转录因子家族包括4个亚家族(HD-ZipⅠ-Ⅳ),其成员通过与其他蛋白互作、参与激素介导的信号途径,从而调控植物生长发育、光形态建成、花发育、果实发育和植物对逆境应答等生物学过程。文章对近几年关于植物HD-Zip转录因子参与上述生物学功能方面的研究进行了综述,以期对新功能基因的挖掘和应用研究以及HD-Zip调控机制的阐明奠定基础。
The HD-Zip transcription factors, which are unique to plant kingdom, belong to Homeobox proteins. They are composed of highly conserved HD （Homeodomain） and Leu zipper （Zip） element. The former binds specifically to DNA and the later mediates the formation of dimerization. Based on the structure features, HD-Zip transcription factors can be classified into four subfamilies HD-Zip I -IV, which are involved in different biological processes of plants including growth and development, photomorphogenesis, flowering, fruit ripening, and adaptation response to environmental stresses. HD-Zip transcription factors act as the integrators of development and environmental cues and endogenous hormone signal pathway to regulate targeted gene expression and plants adaptation response. In this review, the most advanced researcheson biological functions of HD-Zip were summarized based on the researches of Arabidopsis HD-Zip transcription factors and the results from other species. The aim of this article is to provide the basis for studying the functions of new genes encoding HD-Zip proteins from other species and illustrating the molecular mechanism of HD-Zip on growth and develop- ment of plant under normal and unfavorable conditions.
出处
《遗传》
CAS
CSCD
北大核心
2013年第10期1179-1188,共10页
Hereditas（Beijing)
基金
江苏省自然科学基金项目(编号:BK2011674)资助
关键词
HD-Zip转录因子
生物学功能
基因表达
蛋白互作
激素途径
HD-Zip transcription factors
biological functions
gene expression
protein-protein interaction
hor- mone signal pathway
