急性冠状动脉综合征患者血清高敏肌钙蛋白T水平变化及意义被引量：1

Level change of hs-troponin T (hs-TnT) in patients with acute coronary syndrome and its significance

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摘要目的探讨急性冠状动脉综合征(ACS)患者血清高敏肌钙蛋白T(hs-TnT)水平在冠状动脉循环中的变化及其临床意义。方法分别测定和比较ACS患者与对照组冠状静脉窦、冠状动脉血与外周血清中hs-TnT浓度。结果 ACS患者冠状静脉窦、冠状动脉与外周静脉血清中hs-TnT浓度与对照组均有统计学差异(P<0.01),而ACS患者冠状静脉窦血清hs-TnT较冠状动脉血清hs-TnT明显升高(P<0.01)。结论 ACS患者外周静脉、冠状动脉和冠状静脉窦血清hs-TnT浓度明显升高,以冠状静脉窦血清hs-TnT升高最明显。 Objective To investigate the level changes of hs-troponin T （hs-TnT） in patients with acute coronary syndrome （ACS） and its clinical significance. Method The 80 patients with ACS and the 30 patients excluded coronary heart disease（as control） were enrolled in this study.The 110（80＋30） patient＇s blood samples were collected during percutaneous coronary intervention（PCI） from coronary sinus（CS）, coronary artery（CA） and peripheral circulation for detecting concentration of hs-TnT respectively. Result The concentration of hs-TnT in patients with ACS increased significantly in coronary sinus, coronary artery and peripheral circulation than the control groups （P〈 0.01）. The concentration of hs-TnT in coronary sinus were higher than in coronary artery circulation （P〈0.01）. Conclusion The levels of hs-TnT detected in coronary and peripheral circulation as well CS are increased, and that in CS is the most, thus which may be involved in the process of pathophysiology in patients with ACS.

作者陈峰庞继恩孙强盛斌刘志涛刘璟

机构地区 [

出处《实用医药杂志》 2013年第10期865-866,共2页 Practical Journal of Medicine & Pharmacy

关键词急性冠状动脉综合征高敏肌钙蛋白T 冠状动脉循环 Acute coronary syndrome hs-troponin T Coronary circulation

分类号 R541.4 [医药卫生—心血管疾病]

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