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心脏型脂肪酸结合蛋白在心肌梗死诊断中的应用 被引量：5

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摘要 心脏型脂肪酸结合蛋白（H—FABP）是目前新发现的在心脏中含量丰富的胞质蛋白，具有高度的心肌特异性。在心肌缺血的患者中，胸痛发生后血中H—FABP浓度1-3h升高，6～8h达峰，24-30h恢复到正常水平。在心梗患者出现症状24h内检测H—FABP有益于：①更早对患者行再灌注治疗；②检测围手术期心梗：③溶栓治疗30min后判断梗死相关动脉是否再通；④症状发生10h判定是否发生再梗；⑤大体评价心梗面积。作为一种反映心肌损伤的生化标记物，具有广泛的临床应用前景。本文就近年来H—FABP在诊断心肌缺血中的应用作一综述。
作者 刘博 秦永文
机构地区 长海医院心血管内科
出处 《中国心血管病研究》 CAS 2008年第5期397-399,共3页 Chinese Journal of Cardiovascular Research
关键词 心脏型脂肪酸结合蛋白 心肌梗死 诊断 心肌缺血 FABP 梗死相关动脉 心梗面积 临床应用前景
分类号 R542.2 [医药卫生—心血管疾病] R542.22 [医药卫生—心血管疾病]
  • 相关文献

参考文献14

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二级参考文献28

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共引文献41

同被引文献33

引证文献5

二级引证文献16

中国心血管病研究
2008年 第5期

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