摘要
目的 :为探明妊高征血液流变学的变化规律 ,为预防和治疗提供依据。方法 :采用SA -B型体外血栓形成血小板粘附及可调恒压力毛细管粘度计 ,电脑自动测算。对 12 5例妊高征患者进行观察。结果 :①妊高征中期与晚期妊娠血液流变学 9项指标均呈上升趋势 ,其中纤维蛋白原 ,体外血栓长度、湿重、干重 ,血小板粘附率共 5项呈显著升高 ,P <0 .0 5～ 0 .0 1;②妊高征不同程度间血液流变学改变 :血球压积呈逐渐下降趋势 ,血小板粘附率呈逐渐升高趋势 ,两个指标轻度与重度差异显著 ,P <0 .0 5;③妊高征治疗前后血液流变学改变 :治疗后血球压积、全血粘度、血小板粘附率、血沉方程K等 4项呈下降趋势 ;其中血球压积及血沉方程K有显著性差异 ,分别P <0 .0 5～0 .0 1。结论 :血球压积与妊高征治疗密切相关 ;纤维蛋白原、体外血栓长度、湿重及干重 4项指标随着孕周的增加而逐渐增加 ,与妊高征的不同程度成正比 ,与治疗关系不明显 ;血小板粘附率的变化与不同孕期、不同程度密切相关。
Objective:To study the hemorheological changes in pregnant women with pregnancy induced hypertension(PIH),provide foundations for the provention and cure of the PIH.Methods:13 hemorheological parameters including total blood viscosity,reduced total blood viscosity,plasma viscosity(pv),hematocrit(HCT),fibrinogen(Fbg),external thrombus length、Moisture weight、dry weight,Platelet adhesion rates,ante-adhesion platelet counts,post-adhesion platelet counts,ESR and K titer in the ESR equation were examined in cases of PIH.Results:①Fbg,external thrombus length、Moisture weight、dry weight,Platelet adhesion rates were significantly increased in those with mid-pregnant cases compared with late-prenant cases.②HCT was significantly reduced,but Platelet adhesion rate significantly increased in those with severe PIH compared with mild PIH.③HCT and K titer in the ESR equation in the post-treatment cases were significantly lower than those in ante-treatment cases.Conclusion:Variation of HCT possess close relationship with treatment of PIH;Fbg,external thrombus length、Moisture weight、dry weight increased as the number of pregnant weeks,positive related with degree of PIH and no significant correlation with treatment of PIH;Platelet adhesion rate had close relationship with the weeks and degree of PIH.
出处
《赣南医学院学报》
2000年第3期218-221,共4页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
基金
江西省自然科学基金资助课题
