摘要
目的 探讨妊高征血液流变学改变的特点 ,为预防和治疗提供依据。方法 采用SA—B型体外血栓形成血小板粘附二用仪及可调恒压力毛细管粘度计 ,电脑自动测算。结果 (1)妊高征治疗前血液流变学 11项指标中有 5项呈上升趋势 ,其中血球压积、全血粘度、血小板粘附率、血沉方程K值显著升高 ,P <0 .0 5～ 0 .0 1;(2 )妊高征治疗后血液流变学变化规律是 :血球压积、全血粘度、血小板粘附率、血沉方程K值、全血还原粘度、血小板粘附率呈下降趋势 ,其中血球压积和血沉方程K值下降明显 ,P <0 .0 5～ 0 .0 1。 (3 )妊高征产后血液流变学变化规律是 :除血浆比粘度显著升高 ,P <0 .0 5外 ,其余指标均无明显变化 ,P >0 .0 5。结论 血球压积、全血粘度、血小板粘附率和血沉方程K值与妊高征发病密切相关 ;妊高征经过解痉、降压、利尿等一系列治疗后 ,血流变可有明显改善 ;妊高征产后血液流变学变化进一步改善 ,与妊高征产后症状很快消失一致。
Objective To explore the characteristics of hemorheological changes in pregnant women with pregnancy induced hypertension(PIH).Methods 11 hemorheological parameters were examined.Results 1.Hematocrit,total blood viscosity,Paltelet adhesion rates,ESR and K titer were significantly increased in antetreatment cases of PIH compared with late-pregnant cases, P<0.05～0.01. 2.After treatment ,the hematocrit,total blood viscosity,platelet adhesion rates,total blood viscosity,ESR and K titer were gradually decreased,among them the hematocrit and K titer was significantly reduced, P<0.05～0.01. 3.Only the plasma viscosity waw significantly increased in the postpartum cases of PIH compared with normal pregnant,P<0.05,the other parameters showed no obvious difference.Conclusion The changes of hematocrit,total blood viscosity,Platelet adhesion rates,ESR and K titer were close relationship with degree of PIH;after treatment,hemorheology of the PIH may be obviously improved;the hemorheological changes of postpartum had further improvement and correspondent to its clinical presention disappearing.
出处
《江西医药》
CAS
2000年第1期23-25,共3页
Jiangxi Medical Journal
基金
江西省自然科学基金
关键词
正常妊娠
妊娠高血压
血液流变学
比较
pregnancy,normal pregnancy,hemorheology hypertension(PIH) comparative study
