摘要
目的了解地区药品不良反应(ADR)发生的特点及一般规律,为临床合理用药提供参考。方法对上海闸北区392例ADR报告从上报单位分布情况、患者年龄、性别、给药途径、药品种类、新的严重ADR、临床表现等方面进行分析。结果 392例ADR报告中,涉及药品共19类140种,其中抗感染药物最多,有245例(56.32%),其次是中药制剂,有66例(15.17%);静脉滴注给药引发的ADR有342例(78.62%);皮肤及其附件损害为最常见临床表现,有231例(41.03%);新的严重的ADR有28例(7.14%)。结论医务人员应加强ADR监测与报告,促进临床合理用药。
Objective To investigate the characteristics and general pattern of the adverse drug reactions（ADR）occurred in our district, and to provide reference for rational use of drugs in the clinic. Methods A total of 392 ADR cases collected in our district in 2012 were analyzed statistically in respect of patients＇ age and sex, route of administration, drug category, new severe ADR, ADR- involved clinical manifestations,etc. Results Of the total 392 ADR cases, 19 categories or 140 kinds of drugs were involved, antiinfective angents took up the lead place which caused ADRs in 245 cases（56. 32% ）,followed by Traditional Chinese medicine preparation which caused ADR in 66 cases（15. 17% ）. 342 ADR cases（78.62% ）were induced by intravenous administration. Lesions of skin and its appendants were the most common clinical manifestations of the ADR,which appeared in 231 cases（41.03% ）. 28 were new severe cases （7.14%）. Conclusion Medical staff should strengthen the ADR monitoring and reporting so as to promote rational use of drugs in the clinic.
出处
《中国药业》
CAS
2013年第20期67-70,共4页
China Pharmaceuticals
关键词
药品不良反应
分析
合理用药
adverse drug reactions
analysis
rational use of drugs
