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大鼠中枢神经系统衰老的形态学研究:Ⅵ.大脑皮质胶质细胞的超微结构变化 被引量:5

MORPHOLOGIC STUDIES ON THE AGING CHANGES IN CENTRAL NERVOUS SYSTEM OF RAT: Ⅵ. THE ULTRASTRUCTURE OF NEUROGLIA IN CEREBRAL CORTEX
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摘要 对幼年、成年与老年Wistar大鼠大脑躯感皮质的胶质细胞的电镜研究表明:老年大鼠胶质细胞脂褐素增加和卫星化增多;在胶质与神经元胞体之间,神经元的胞质膜和胶质贴近处出现表面下复合器的情况也增多。星形胶质细胞还有胞质肥大和微丝增多的倾向。在个别老年动物中见到一种特殊的多层平行膜板状髓鞘样结构出现于胶质与神经元胞体之间。 The cerebral cortices of Krieg's 2 area from young, adult and senescent Wistar rats were studied ultramicroscopically. The morphologic changes of neroglia in these three groups of animals demonstrated that the amount of lipofuscin pigment in glia cells and the frequency of glia satellitosis increased in the old rats. The subsurface complex (SSC) in some sites of neurons, where the neuroglial cells attached, occurred more frequently and more complex in structure in the old rats than those in the adult ones. The SSCs had rarely been seen in the young animals. In an old rat, an unusual myelin-like membraneous body was observed between an oligodendrocyte and a neuron. Some astrocytes in the old rats showed somewhat hypertrophied cytoplasm and increased microfilaments. Other obvious intracellular changes could not be found in the present study.
出处 《动物学报》 SCIE CAS CSCD 1991年第2期210-215,共6页 ACTA ZOOLOGICA SINICA
关键词 大鼠 衰老 大脑皮质 超微结构 Rat, Aging, Cerebral cortex, Neuroglia, Ultrastructure.
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参考文献3

  • 1侯家骥,动物学报,1988年,34卷,144页
  • 2黄世楷,神经生理学手册.3,1985年
  • 3侯家骥,解剖学报,1983年,14卷,191页

同被引文献13

  • 1赵增翰.脑的衰老[J].神经解剖学杂志,1988(1):1-9. 被引量:2
  • 2王荣华.衰老时人大脑皮质脂褐素体的超微结构研究[J].解剖学杂志,1993,16(2):105-109. 被引量:4
  • 3张兵,侯家骥.大鼠海马CA_1区锥体神经元在衰老过程中的超微结构变化[J].神经解剖学杂志,1995,11(3):249-252. 被引量:13
  • 4侯家骥,刘志勋.大鼠中枢神经系统衰老的形态学研究 Ⅲ、大脑锥体细胞与小脑浦氏细胞的脂褐素沉积[J]兰州医学院学报,1984(03).
  • 5Deborah W. Vaughan,Alan Peters. Neuroglial cells in the cerebral cortex of rats from young adulthood to old age: An electron microscope study[J] 1974,Journal of Neurocytology(4):405~429
  • 6Deborah W. Vaughan,Alan Peters. Neuroglial cells in the cerebral cortex of rats from young adulthood to old age: An electron microscope study[J] 1974,Journal of Neurocytology(4):405~429
  • 7Dr. Fritz-H. Güldner. Synaptology of the rat suprachiasmatic nucleus[J] 1976,Cell and Tissue Research(4):509~544
  • 8I. J. Bak,W. B. Choi. Electron microscopic investigation of synaptic organization of the trochlear nucleus in cat[J] 1974,Cell and Tissue Research(3):409~423
  • 9F. -H. Güldner,J. R. Wolff. Multi-lamellar astroglial wrapping of neuronal elements in the hypothalamus of rat[J] 1973,Experientia(11):1355~1356
  • 10Manuel B. Grabber,Georg W. Kreutzberg. Astrocytes increase in glial fibrillary acidic protein during retrograde changes of facial motor neurons[J] 1986,Journal of Neurocytology(3):363~373

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