摘要
目的 :通过多孔块状β-磷酸三钙 (β- TCP)对兔颅骨缺损的修复 ,定量测量其在体内的吸收速度。方法 :2 4只家兔随机分为 2 ,4,8,12周 4个时间点组 ,每组 6只动物 ,分别将β- TCP及羟基磷灰石 (HA)样本种植在兔左右顶骨的缺损处 ,于术后 2 ,4,8,12周取材 ,采用“数点法”计算各组材料的剩余量。结果 :12周时β- TCP组材料剩余 34.5 4% ,材料吸收了 40 .0 1%。结论 :多孔块状β- TCP陶瓷作为骨代用品 ,不失为一种较好的材料。
砄bjective:To study the absorption of porous block β tricalcium phosphate(β TCP) implanted in the defects of rabbit calvarium.Methods:Twenty four rabbits were randomly divided into four groups with six in each,a round piece of bone with the diameter of 8 mm was removed on left and right sides in the calvarium of each animal.β TCP samples were implanted in the left defects and hydroxyapatite(HA)in the right.Rabbits were sacrificed at 2,4,8,12 weeks after operation respectively,The implanted materials were quantitatively measured by "Point Counting".Results:Twelve weeks after operation,the amount of β TCP and HA remained in the transplants were 34.54% and 49.28%,while the bone tissue comprised 24.43% and 19.67% of β TCP and HA transplants respectively.Conclusion:Porous block β TCP is more absorbable and more feasible for new bone tissue regeneration than HA.
出处
《实用口腔医学杂志》
CSCD
北大核心
2000年第6期451-452,共2页
Journal of Practical Stomatology
