摘要
目的 研究肺动脉是否参与肺癌的血供及肺动脉在肺癌中的形态学和血流状况的改变。方法 用 2种颜色的硅酮灌注 33只大白鼠肺鳞癌模型的支气管动脉和肺动脉 ,在手术显微镜下整体和立体地观察肺癌的血供来源和肺动脉的形态改变。 2 8例肺癌患者同时行支气管动脉和肺动脉的数字减影血管造影检查。结果 肺癌大鼠和患者所有的肺动脉在肺癌区域减少、缩小、消失 ,肺动脉不形成肿瘤血管。肺癌所在区域内、肺动脉血流以段和叶为单位灌注不足或无血流灌注。结论肺动脉不参与肺癌供血 。
Objective To investigate whether or not the pulmonary artery participates in the blood supply of lung cancer and its change of morphology and blood flow in lung cancer. Methods Two different colors of silicone were injected separately into the bronchial and pulmonary arteries of 33 rat models with squamous cell carcinoma of lung. The origin of blood supply of lung cancer and the morphologic change of pulmonary artery were observed under a stereomicroscope. The DSA of bronchial and pulmonary artery were performed simultaneously in 28 patients with lung cancer. Results The pulmonary branch of rat and patients were reduced, thinned and occluded in the affected lung. The pulmonary artery did not form tumor vessel, and pulmonary blood flow and perfusion were reduced or absent in the affected area. Conclusion The pulmonary artery didn′t participate in the blood supply of lung cancer. It is unreasonable to perform transcatheter chemo embolization for lung cancer via pulmonary arteriay.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2000年第12期802-804,共3页
Chinese Journal of Radiology
基金
国家"九五"攻关课题资助项目 !(96 90 7 0 3 0 3)
关键词
肺癌
肺动脉
供血
数学减影血管造影
Lung neoplasms
Animals, laboratory
Angiography, digital subtraction
Evaluation studies
