摘要
目的探讨慢性阻塞性肺疾病患者痰真菌培养阳性与并发持续型喘息的相关性。方法选取南京医科大学附属江宁医院内科及江苏省人民医院呼吸科收治的符合研究纳入标准的慢性阻塞性肺病的患者100例,并根据患者是否有持续型的喘息症状,将所有患者分为喘息组和对照组各50例,对以上患者的临床资料及痰培养的结果进行分析总结。结果痰培养检出病原菌喘息组61株、对照组37株,曲霉菌属的检出率喘息组患者为9.84%、对照组为0,两组比较差异有统计学意义(P<0.05);喘息组患者的真菌培养结果阳性率68.00%,明显高于对照组的16.00%,差异有统计学意义(P<0.05);而两组患者痰培养结果中,细菌培养阳性率比较,差异无统计学意义。结论慢性阻塞性肺疾病患者肺部的真菌感染,尤其是曲霉菌属的感染可能是导致患者出现持续型喘息的原因之一。
OBJECTIVE To investigate the correlation of positive sputum culture of fungi and concurrent continuous wheeze in patients with chronic obstructive pulmonary disease. METHODS A total of 100 patients with chronic obstructive pulmonary disease were selected in Jiangning Hospital Affiliated to Nanjing Medical University and the Department of Respiration in the First People＇s Hospital of Jiangsu Province. According to whether the patient had persistent wheezing symptoms, the patients were divided into wheeze group and control group with 50 cases in each group. The clinical data of the patients in these two groups were retrospectively analyzed and summarized. RESULTS A total of 61 strains in the wheeze group and 37 strains in the control group were detected by sputum culture. The detectable rate of Aspergillus for the wheeze group was 9.84 %, significantly higher than the control group （0）（P〈0.05） The positive rate of sputum fungal culture in the wheeze group was 68.00%, significantly higher than the control group （16.00 %）, the difference was significant （P〈0.05） for the bacterial culture, no difference in the positive rate was observed between the two groups. CONCLUSION Pulmonary fungal infections in chronic obstructive pulmonary disease patients, especially Aspergiilus infections, may be one important reason that leads persistent wheezing.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第19期4647-4649,共3页
Chinese Journal of Nosocomiology
关键词
慢性阻塞性肺疾病
持续型喘息
痰真菌培养
相关性
Chronic obstructive pulmonary disease
Persistent wheezing
Sputum fungal culture
Correlation
