摘要
背景急性肾损伤（acute kidney injury，AKI）是外科重症患者术后常见并发症之一，其发病率和死亡率均较高，严重地威胁了患者的生命安全。目的为了早期有效识别和诊断外科重症患者术后发生的AKI并及时地提供诊治措施以降低AKI的发病率、改善这类患者的结局。现就这类新型标记物的研究进展作一综述。内容主要针对外科重症患者，探讨新型标记物检测在其灵敏性和特异性以及AKI病情评估方面相对于传统检测的优势。趋向未来对于外科重症具有高AKI风险因素的患者采用新型标记物外科联合检测将有利于术后AKI的早期诊断和预后评估。
Background As one of common postoperative complications in critically ill surgical patients, the incidence and mortality of acute renal injury were higher, and which seriously threaten the safety of surgery patients. Objective This article reviews the research progress of the novel markers, in order to timely identify and diagnose acute kidney injury （AKI）, reduce the incidence of postoperative AKI, improve the outcomes of surgical critically ill patients with AKI. Content To evaluate the sensitivity and specificity of novel markers for AKI, and compare its superiority of diagnosis for AKI with the traditional detection in surgical critically ill patients Trend Using combined detection with novel markers will be good for early diagnosis and prognosis evaluation of postoperative AKI in critically ill patients with high risk factors of AKI in the future.
出处
《国际麻醉学与复苏杂志》
CAS
2013年第10期932-935,共4页
International Journal of Anesthesiology and Resuscitation
