摘要
目的:评估系统性红斑狼疮(SLE)合并动脉粥样硬化的发生率及相关危险因素。方法:采用颈动脉多普勒超声检测30例SLE病人(SLE组)及30名健康女性(对照组)颈部动脉粥样硬化斑块发生情况,并对其血清中总胆红素(TB)、尿酸(UA)、同型半胱氨酸(Hcy)等与SLE合并动脉粥样硬化之间的关系进行分析。结果:SLE组动脉粥样硬化的危险因素肥胖,尿酸、同型半胱氨酸的水平显著高于正常组,且SLE组中有斑块组这些危险因素的水平比无斑块组明显增高。结论:SLE患者并发动脉粥样硬化的发生率显著增高,而肥胖、尿酸、同型半胱氨酸则是可以反映SLE并发动脉粥样硬化的风险的相关危险因素。
Objective：To evaluate incidence and risk factors for atherosclerosis in patients with SLE. Methods：The prevalence of atherosclerotic plaque on the neck in 30 women with SLE and 30 healthy controls were examined by ultrasonography. The relation- ship between the atherosclerosis risk factors such as obesity, UA, Hcy and the atherosclerosis in patients with SLE was studied. Re- sults ： SLE group atherosclerosis risk factors for obesity, UA, Hcy were significantly higher than normal group. And compared with the group without plaque, the levels of these risk factors of the plaque group in SLE group were increased significantly. Conclu- sion：The incidence of atherosclerosis in patients with SLE with is significantly increased. And risk factors such as UA, HCYmay reflect the risk of concurrent arterial atherosclerosis in SLE.
出处
《亚太传统医药》
2013年第9期88-90,共3页
Asia-Pacific Traditional Medicine
