摘要
目的:探讨经胸食管癌根治术后采用早期肠内营养支持对小肠运动功能的影响。方法:选择2010年1月至2012年11月行经胸食管癌根治术患者80例,完全随机均分为A(早期肠内营养)组和B(对照)组,每组40例。记录术前、术后10日两组患者体重。观察两组术后肠道蠕动、排气、排便时间。观察记录术后恶心呕吐、腹胀、腹泻等不良反应发生率。结果:与B组相比较,A组术后肠蠕动[(21.77.3)h比(29.66.9)h]、排气[(31.58.6)h比(38.27.8)h]、排便时间[(43.29.7)h比(56.18.4)h]B组明显提前,差异有统计学意义(t=4.662,P=0.000;t=3.650,P=0.001;t=6.358,P=0.000);A组术后10天的体重[(55.8±10.1)kg比B组(50.6±11.5)kg]明显增加,差异有统计学意义(t=0.163,P=0.035)。两组术后恶心呕吐、腹胀、腹泻不良反应发生率无明显差别,差异无统计学意义(x2=0.092,P=0.762;x2=0.346,P=0.556;x2=0.621,P=0.431)。结论:经胸食管癌术后采用早期肠内营养支持安全有效,不增加并发症发生率,可促进小肠运动功能恢复,有效增加患者体重。适合临床推广应用。
Objective：To explore the effect of intestinal motor function by early enteral nutrition after esophagectomy. Methods：80 patients from January 2010 to November 2012 with esophageal cancer were randomly divided into two groups, Group A （early enteral nutrition,n= 40）and Group B （control group,n=40）.The patients weight of the two groups were recorded in preoperative and 10 days after surgery. The time of intestinal peristalsis,exhaust and defecation were observed in postoperative. The incidence of adverse reactions postoperative of nausea and vomiting,abdominal distension, diarrhea, etc were observed and recorded.Results：The time of postoperative bowel[（21.77.3）h], exhaust[（31.58.6）h], defecation[（43.29.7）h] were significantly earlier in group A than that[（29.66.9）h;（38.27.8）h;（56.18.4）h] in group B,the difference was statistically significant（t=4.662,P=0.000;t=3.650,P=0.001;t=6.358,P=0.000）. 10 days after surgery,the weight of pantiens[（55.8±10.1）kg] were increased significantly in group A compared with the group B[（50.6±11.5）kg], the difference was statistically significant（t=0.163,P=0.035）.It was no significant difference about the incidence of adverse reactions in the two group, the difference was not statistically significant（x2=0.092,P=0.762;x2=0.346,P=0.556;x2=0.621,P=0.431）.Conclusion：Early postoperative enteral nutrition for esophageal cancer is safe and effective.It does not increase the incidence of complications. It is not only improving the patient＇s weight and promoting intestinal motor function recovery,but also does not increasing the incidence of complications.It is suitable for clinical application.
出处
《中国医药导刊》
2013年第9期1434-1435,共2页
Chinese Journal of Medicinal Guide
关键词
食管癌
早期肠内营养
小肠运动功能
Esophageal cancer Early enteral nutrition Intestinal motor function
