摘要
目的探讨优泌乐25及诺和锐30在治疗2型糖尿病中的疗效。方法 60例经口服降糖药治疗效果不佳的2型糖尿病患者分为优泌乐25治疗组及诺和锐30治疗组,在继续服用原有降糖药的基础上,分别采用每日2次注射上述两种胰岛素降糖12周后,对两组患者的空腹血糖、早餐后2h的血糖、糖化血红蛋白、胰岛素日均用量和低血糖情况进行比较。结果(1)治疗后两组患者的空腹血糖、早餐后2h的血糖、糖化血红蛋白均较治疗前明显下降(P<0.05)。(2)治疗后两组患者的胰岛素日均用量及低血糖发生率差别无统计学意义。(3)优泌乐25组空腹血糖水平低于诺和锐30组空腹血糖水平(P<0.05),而诺和锐30组早餐后2h血糖水平低于优泌乐25组(P<0.05),差异有统计学意义。结论对于2型糖尿病患者而言,使用优泌乐25及诺和锐30均能较好的控制血糖且稳定,不易发生低血糖反应,使用优泌乐25能较好的控制空腹血糖,而诺和锐30能较好地控制早餐后2h血糖。
Objective To investigate the effects of twice subcutaneous injections of mixed insulin analogue lilymix25 and mixed insulin analogue novomix30 on treating type 2 diabetes. Methods 60 cases of DM2 patients who lost the effectiveness of oral medicines were divided into two groups, given mixed insulin analogue lilymix25 and novomix30 respectively,based on continued to take the oral medicines,and observed for 12weeks. Results （1）The fasting blood- glucose,the postprandial blood-glucose 2 hours after the breakfast and HbA1C of both two groups were lower than before treating, the difference has statistical significance（P 〈 0.05）.（2）The average daily dose of insulin and the incidence of low blood-glucose in both two groups has no significant differences.（3）The fasting blood-glucose levels in group A was less than group B,the difference has statistical significance（P 〈 0.05）.And the postprandial blood- glucose 2 hours after the meal in group B was less than group A, the difference has statistical significance（P 〈 0.05）. Conclusion Mixed insulin analogue lilymix25 and novomix30 can effectively reduce the fasting blood-glucose,the postprandial blood-glucose 2 hours after the meal and HbA1C,lower the incidence of low blood-glucose. Mixed insulin analogue lilymix25 can control the fasting blood-glucose better and mixed insulin analogue novomix30 can control the postprandial blood-glucose 2 hours after the breakfast better.
出处
《中国医药科学》
2013年第17期87-89,共3页
China Medicine And Pharmacy
关键词
优泌乐25
诺和锐30
2型糖尿病
Mixed insulin analogue lilymix25
Mixed insulin analogue novomix30,Type 2 diabetes mellitus
