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赖诺普利联合前列地尔治疗血压正常的早期糖尿病肾病疗效观察 被引量:4

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摘要 目的观察赖诺普利联合前列地尔治疗血压正常的早期糖尿病肾病(DN)的疗效。方法DN患者35例,随机分为常规组18例和联合组17例,在胰岛素降糖、抗凝治疗基础上,常规组加用赖诺普利,联合组加用赖诺普利和前列地尔,治疗4周,观察治疗前后血压、糖化血红蛋白(AbA1c)、24 h尿微量白蛋白量(UARE)和肌酐(Cr)变化。结果 2组24 h UARE均下降(P<0.05),与常规组比较,联合组下降明显(P<0.01)。结论赖诺普利联合前列地尔可明显减少血压正常的早期DN患者的24 h UAER排泄量,延缓DN进展,具有临床价值。
出处 《河北医药》 CAS 2011年第22期3394-3395,共2页 Hebei Medical Journal
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