摘要
目的研究白内障摘除术患者术后5年手术眼与对侧眼老年性黄斑变性（AMD）发病情况。方法选取2004—2006年在仙居县人民医住院行单眼白内障摘除术的患者221例，随访60个月以上，比较患者手术眼与对侧眼AMD发病情况。结果共有132例完成随访，随访率为59．70％。白内障摘除术后3个月患者脱残率为80．30％（106／132），脱盲率为99．20％（131／132）。术后5年手术眼AMD总发病22例（16．67％），对侧眼总发病20例（15．15％），差异无统计学意义（x2=0．11，P〉0．05）。其中轻度AMD的OR值为1．092，95％C10．479—2．492；中度AMD的OR值为1．187，95％C10．387～3．644；重度AMD的OR值为1．188，95％C10．387—3．647；总AMD的OR值为1．120，95％C10．579～2．167。结论白内障摘除术患者术后5年手术眼与对侧眼AMD发病情况差异无统计学意义，白内障摘除术不是患者术后5年AMD发病的危险因素。
Objective To study the incidence of age-related macular degeneration （AMD） in operated and nonoperated eyes of patients received cataract surgery. Methods 221 cataract patients in the people＇s hospital of Xianju county from 2004 to 2006 were selected and followed for at least for 60 months after surgery. The incidence of AMD in operated and nonoperated eyes were compared. Results 132 patients （59.70%） were followed for at least 60 months. 3 months after cataract surgery, the take-off residual rate was 80.30% （ 106/132）, the literacy rate was 99.20% （131/132）. 5 years after catarct surgery, the incidence of AMD in operated and nonoperated eyes were 16. 67% （ 22/132 ） and 15.15 % （20/132）, the difference was not significant （ x^22 = 0.11, P 〉 0.05 ）, OR was 1. 120, 95 % CI 0.579 - 2. 167. In mild AMD, OR was 1. 092,95 % CI 0. 479 - 2. 492 ;moderate AM D OR was 1.187,95 % CI 0. 387 - 3. 644 ;severe AMD OR was 1. 188,95% CI 0. 387 - 3. 647. Conclusion Cataract surgery did not increase the the risk of AMD over 5 years.
出处
《中国基层医药》
CAS
2013年第22期3432-3433,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
白内障摘除术
黄斑变性
老年人
Cataract surgery
Age-related macular degeneration
Elderly
