摘要
目的 :研究同种异体血管移植在建立透析通路中的应用。方法 :将经冷冻、干燥和辐射处理后的人尸血管移植于 52例尿毒症患者前臂和上臂 ,建立永久性血管透析通路。结果 :手术成功率和术后 3～ 4周移植动静脉内瘘使用率均为 1 0 0 % ;至今 44例仍保持通畅 ,其中 2～ 3年 9例 ,1～ 2年 1 9例 ,不足 1年 1 6例 ,8例移植血管已失去功能 ,主要原因为血栓形成 5例 ,发生动脉瘤 2例 ,感染 1例。结论 :冻干辐射血管取材方便 ,价格低廉 ,容易保存 ,无抗原性 ,用于移植动静脉内瘘手术简单 ,成功率高 ,为自身动静脉内瘘建立困难的维持性血液透析患者提供了理想的移植血管通路。
Purpose:To explore the application of vascular allografts for hemodialysis access. Methods:Freezing-dried and irradiated human cadaveric vascular grafts were placed in forearm or upper arm as permanent hemodialysis vascular access in 52 patients with uremia.Results:Immediate patency rate was 100%. All grafts were performed in 3~4 weeks after operation. Among the 44 grafts still being used hitherto, 9 grafts had been used for 2~3 years, 19 for 1~2 years and 16 in 1 year. Other 8 grafts failured due to complications : thrombosis (5 cases)、aneurysm (2 cass) and infection (1 case).Conclusions:Freezing-dried and irradiated vascular allografts were inexpensive, easy to approach and preserve and, with no antigenicity. The allograft is easy to manage during surgery and with high patency rate when it was used for hemodialysis access. It was indicated that freezing-dried and irradiated vascular allograft is a good alternative in case of direct A-V fistula failure or inability to perform a direct A-V anastomosis in patients undergoing hemodialysis.
出处
《临床泌尿外科杂志》
2000年第10期451-452,共2页
Journal of Clinical Urology
关键词
血管移植
血液透析
冷冻
干燥
辐射
尸体
Blood vessels transplantation Hemodialysis Freezing Desiccation Radiation Cadaver
