摘要
目的 :研究术后放疗对面神经损伤恢复的影响。方法 :将 1995— 1997年间腮腺肿瘤术后出现面瘫的2 0名患者分成单纯手术组 (operationgroup ,以下简称O组 ) 6例和术后放疗组 (operationandradiationgroup ,以下简称OR组 ) 14例。OR组于术后 4周内放疗 ,以手术日至面瘫完全消失所需时间比较两组面神经功能恢复的差异。结果 :经术后 4周 48— 6 1Gy常规放疗 ,腮腺肿瘤术后面神经损伤的恢复基本不受影响。OR组肿瘤量平均 5 5 91±3 6 4Gy。面神经平均恢复时间O组为 6 4月 ,OR组为 9月 ;经t检验 ,两组结果无显著性差异 ,P =0 10 5。肿瘤累及的面神经 ,经术中保留术后放疗 ,其功能可完全恢复 ,面瘫消失时间平均 8 4月。除 1例腮腺恶性淋巴瘤出现远处转移外 ,其余均未出现局部复发和远处转移。结论 :包括 5 0岁以上的腮腺恶性肿瘤患者 ,面神经解剖术造成的面瘫 ,经术后常规放疗 ,术后 9个月左右恢复正常 ,不致产生永久性面瘫。
Purpose:To study the affect of radiation on restoration of facial nerve lesion.Methods:This study included 20 patients suffering from paralysis after parotid tumor operations during 1995—1997.They were divided into two groups, operation group (O group) with 6 cases and radiation group (OR group) with 14 cases. Routing radiation was give 4 weeks after operation in OR group. We compared the differences of times of facial nerve function restoration between the two groups. Results:After postoperative radiation, the restoration of facial nerve lesion was not affected. The mean tumor dose of the group was 55.91±3.64 Gy,and the mean time of restoration of facial nerve lesion was 6 months for O group and 9 months for OR group, P =0 105. The function of facial nerve involved by tumor could be restorable completely after postoperative radiation. The mean time for disappearance of paralysis needed 8.4 months in these case. Except for one metastasis, occurring in a patient suffering from lymphoma, no recurrence and metastasis occurred in any other patients.All patients could work or live normally after combined therapy. Conclusions:Our results suggested that facial nerve lesion could be restored in 9 months after routine psotoperative radiation in patients suffering from parotid carcinoma, even if facial nerve was involved by tumor. It is possible to resect the parotid tumor radically and preserve the facical nerve and its function simultaneously.
出处
《中国癌症杂志》
CAS
CSCD
2000年第5期419-420,共2页
China Oncology
