摘要
[目的]探讨影响腮腺癌治疗效果及预后的因素。[方法]回顾分析284例腮腺癌临床资料,分析性别、年龄、病理类型、临床分期及治疗方法等对5年、10年生存率的影响。[结果]全组病例5年、10年生存率分别为73.2%、52.0%。单因素分析显示病理类型(P=0.03)、临床分期(P=0.00)、面神经是否受累(P=0.00)是腮腺癌生存的预后因素,年龄(P=0.08)、性别(P=0.06)对腮腺癌预后无显著影响。原发灶首次单纯手术与手术加术后放疗相比较生存率差异无统计学意义(P>0.05),但两组与再次手术及再次手术+放疗组比较生存率差异具有统计学意义(P<0.05)。[结论]手术是治疗腮腺癌的主要手段,首次手术、临床分期、病理类型及面神经是否受累是影响腮腺癌治疗效果及预后的重要因素。
Purpose To investigate the influence factors of the therapeutic efficacy and prognosis of parotid gland carcinoma. Methods Data of 284 cases with parotid gland carcinoma were analyzed retrospectively. The influences of gender,age,pathological types,clinical stages and therapeutic methods,etc. on 5- and 10-year survival rates of parotid gland carcinoma were analyzed. Results Of all the cases,the 5-and 10-year survival rates were 73.2% and 52.0%. Univariate analysis showed that pathological type （P=0.03）,clinical stage （P=0.00）,and facial nerve involvement （P=0.00） were prognostic factors for parotid gland carcinoma. Age （P=0.08） and gender （P=0.06） had no significant influence on prognosis of parotid gland carcinoma. Survival rate had no significant difference between patients initially treated with surgery alone and those with surgery plus postoperative radiotherapy for primary lesion（P0.05）,but survival rates of the patients in the two groups were significantly different with those of secondary treatment （P0.05）. Conclusions Surgery is the commonest treatment for parotid gland carcinoma. Initial surgery,clinical staging,pathological type and facial nerve involvement are important influencing factors for prognosis of parotid gland carcinoma.
出处
《肿瘤学杂志》
CAS
2013年第6期466-469,共4页
Journal of Chinese Oncology
关键词
腮腺肿瘤
治疗
生存率
外科手术
parotid gland neoplasms
treatment
survival
surgery
