摘要
目的研究并发原发性高血压的不同脑血管病病人脑微出血(CMBs)的发生率、分布特点、严重程度,并分析CMBs与血压控制的关系。方法并发原发性高血压的脑卒中病人77例,包括脑出血组33例,脑梗死组44例;对照组34例,为同期住院的并发原发性高血压的非脑血管病病人。记录各组CMBs病灶的部位、数量及病人平时平均收缩压。结果脑出血组CMBs的发生率最高(63.6%),严重程度以中度和重度为主;其次为脑梗死组(31.8%),严重程度以轻度和中度为主;对照组发生率最低(8.8%),均为轻度。CMBs病灶共检出576个,位于脑叶211个(36.6%)、大脑半球深部326个(56.6%)、小脑幕下39个(6.8%)。CMBs病灶数量与病人平时平均收缩压呈正相关(r=0.791,P<0.01)。结论并发高血压的脑卒中特别是脑出血病人CMBs的发生率较高,并且病灶多见于深部脑组织。CMBs病灶数量与病人平时平均收缩压呈正相关,这提示血压控制对并发高血压的CMBs病人是非常重要的。
Objective To investigate the incidence, distribution and severity of cerebral microbleeds （CMBs） in different cerebral vascular diseases （CVDs） and analyze their relationship with their blood-pressure control. Methods Seventy-seven pa- tients with intracerebral hemorrhage （ICH） including 33 in ICH and 44 in cerebral infarction （CI） due to primary hypertension （PH） were enrolled. A control group consisted of 34 PH patients without CVDs. The locations of CMBS, numbers and the pa- tients＇ systolic pressure in normal time were recorded. Results The incidence of CMBs was the highest （63.6%） in the ICH, the severity being moderate and severe; followed by the CI （31.8%）, the severity was mild to moderate; the least incidence was noted in the control （8.8%）, with mild in degree. A total of 576 CMB lesions were detected, of which, 211 （36.6%） were located in lobe of brain, 326 （56.6%） in deep part of cerebral hemisphere, and 39（6.8%） in infratentorial region. The numbers of CMBs were positively correlated with the patients＇ systolic pressure in normal time （r=0.791,P〈0.01）. Conclusion The incidence of stroke in hypertensive patients, CMBs in particular, is relatively high, the lesions are mostly seen in deep part of brain tissue. The numbers of the focus were positively correlated with the normal time systolic pressure of the patients, indicating that the control of blood pressure is very important for this type of patients.
出处
《青岛大学医学院学报》
CAS
2013年第5期441-442,445,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
高血压
脑血管疾病
微出血
磁共振成像
hypertension
cerebrovascular disorders
microbleedst magnetic resonance imaging
