摘要
目的探讨原发性高血压(EH)病人微量清蛋白尿(MAU)与颈动脉内膜中层厚度(IMT)的相关性。方法 EH病人92例,按照尿微量清蛋白(UmAlb)水平分为两组,MAU组38例,正常组(NAU组)54例,应用超声检查两组病人颈动脉IMT,并检测尿素氮(BUN)、肌酐(Cr)、尿酸(UA)、三酰甘油(TG)、低密度脂蛋白(LDL-C)和UmAlb水平,进行相关性分析。结果 MAU组病人的尿Cr水平、颈动脉IMT及斑块形成率均高于NAU组,差异有显著性(t=22.598、21.730,χ2=4.165,P<0.05)。EH病人颈动脉IMT与MAU呈正相关(r=0.415,P<0.01)。结论 EH病人MAU水平可能是反映动脉粥样硬化及硬化程度的敏感指标,可作为动脉粥样硬化的一项危险预测因素。
Objective To explore the correlation between microalbuminuria （MAU） in patients with essential hyperten- sion （EH） and carotid intima-media thickness （IMT）. Methods Ninety-two EH patients were divided into two groups as MAU group （38 cases） and non-MAU group （54 cases） according to the level of MAU. The carotid IMT of the patients was measured by color Doppler uitrasonography. BUN, Cr, UA, TG, LDL-C, and MAU were detected. A correlation analysis was done. Results The level of Cr, the carotid IMT and formation rate of plaque in MAU group were higher than that in non-MAU group, the diffe- rences being significant between the two groups （t =22.598,21.730;X^2=4.165;P〈0.05）. The IMT was positively correlated with MAU in EH patients （r=0.415 ,P〈0.01）. Conclusion The level of MAU in patients with EH is likely to be a sensitive marker reflecting atherosclerosis and its degree, which can be used to predict the risk factor of the disease.
出处
《青岛大学医学院学报》
CAS
2013年第5期431-432,435,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
高血压
颈动脉疾病
清蛋白尿
超声检查
多普勒
彩色
hypertension
carotid artery diseases
albuminuria
ultrasonography, Doppler, color
