摘要
该文围绕本实验室参与推导的中药通用提取动力学模型,建立了适当试验以及数据处理方法,并以葛根总黄酮为测定指标,以水煎煮法提取葛根中总黄酮对该模型的适应性进行了研究。研究发现,葛根总黄酮质量浓度的自然对数值随时间、溶剂倍量值的自然对数变化成良好线性关系,通过计算,拟合,成功地建立了水煎煮法提取葛根总黄酮的动力学模型,并对该模型进行了验证,拟合度良好,偏差能够很好地控制在工业生产要求的范围内,说明该方法的模型适应性良好。但方程校正因子仍需进一步研究。
To establish an appropriate experimental and data processing method on the basis of the general kinetic model for extraction of traditional Chinese medicines, in order to study the effect of total flavonoids in water extracts from Puerariae Radix on the adaptability of the model, with total flavonoids of Puerariae Radix as the determination indicator. The results showed that the natural logarithm of mass concentration of total flavonoids showed a good linearity with the changes in extraction time and solvent volume. Through calculating and fitting, we successfully established the kinetic model for water extraction of total flavonoids from Puerariae Ra- dix, and verified its accuracy. Its good fitting degree and controllable deviation within the range of industrial production requirements indicated a good adaptability of the model. However, its equation correction factors require further studies.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2013年第17期2788-2792,共5页
China Journal of Chinese Materia Medica
基金
国家自然科学基金面上项目(81173563)
关键词
提取动力学模型
葛根
模型适应性
总黄酮
kinetic model for extraction
Puerariae Radix
model adaptability
total flavonoids
