摘要
本文采用高效液相色谱法建立了血浆中黄豆甙元的含量测定方法,研究了黄豆甙元及其固体分散物在人体内的生物利用度并求得药物动力学有关参数。结果表明黄豆甙元固体分散物胶囊相对市售胶囊的相对生物利用度为504%.
An HPLC analysis method for daidzein level in plasma was established. The bioavailability was studied in human volunteers.A significant difference was observed in human body in bioavailability parameters between daidzein solid dispersion and daidzeiu after oral administration of the same dosage, Daidzein solid dispersion showed better bioavailability than daidzein.
