摘要
目的:建立替曲朵辛中金属元素的测定方法。方法:采用微波消解-ICP/MS法测定替曲朵辛中的Al、Mn、Ni、As、Pb、V、Fe、Cu、Cd、Cr、Co、Zn和Ba共13种金属元素。结果:方法检出限为0.03～1.5×10-9g.g-1,牛肝标准物质加标回收率在85%～109%,各元素线性关系良好。结论:微波消解-ICP/MS法用量少、检出限低、分析速度快、能同时分析替曲朵辛中多种元素。
Objective： To establish a method for determination of heavy metal elements in tetrodotoxin.Methods： ICP / MS was used to determine 13 metal elements in tetrodotoxin,including Al,Mn,Ni,As,Pb,V,Fe,Cu,Cd,Cr,Co,Zn and Ba.Results： The method detection limits for all target elements were with a range of 0.03-1.5 × 10-9 g.g-1,while the recovery values ranged from 85% to 109%.The correlation coefficients were good.Conclusion： The microwave digestion-ICP / MS method has a low detection limit,a fast analysis rate and it only requires a small amount of sample which can simultaneously analyze various elements in tetrodotoxin.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2013年第8期1382-1384,共3页
Chinese Journal of Pharmaceutical Analysis
