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癫样放电在抗癫药物应用及复发预测中的意义 被引量:1

Significance of epileptiform discharges in anti-epileptiform drug therapy and prediction of relapse
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摘要 癫首次发作后脑电图检出癫样放电异常率在儿童为18%~56%,成人为10%~50%,脑电技术是最常用的癫神经病学检查手段,特征性脑电图异常能够帮助对发作类型及癫综合征的分类、确定治疗方案及判断预后。在特定病例,脑电图能检测到更加细微的发作,包括失神、肌阵挛或部分性发作。癫治疗中不同的抗癫药物对癫样放电的抑制存在差异,癫样放电在复发预测及决定撤除抗癫药物方面起着重要作用。 EEGs performed for new-onset seizures show epileptiform discharge in approximately 18% to 56% of children and 12% to 50% of adults.EEG is the most commonly used means of neurological examination for epilepsy.Specific EEG abnormalities help characterize the seizure type and epilepsy syndrome,which allows more informed decisions regarding therapy and more accurate prediction of seizure control and ultimate remission.In certain cases,the EEG may detect more subtle seizures,including absence,myoclonic or partial seizures.In the therapy of epilepsy,the effect of different antiepileptic drugs on the inhibition of epileptiform discharges is different.Epileptiform discharges play a very important role in the prediction of recurrence and the decision to remove antiepileptic drugs.
作者 袁凯杰 侯梅
出处 《临床儿科杂志》 CAS CSCD 北大核心 2013年第8期788-790,共3页 Journal of Clinical Pediatrics
关键词 癫痫 抗癫痫药物 撤药 复发预测 epilepsy anti-epileptiform drugs withdraw prediction of relapse
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