4TREIMAN D M. Generalized convulsive status epilepticus in the adult[ J]. Epilepsia,1993,34 ( Suppl. 1 ) :2-11.
5LOTT R S. Seizure disorders. In: Koda-Kimble,A. M. (Ed.), Applied Therapeutics : The Clinical Use of Drugs. Washington : Applied Therapeutics, Inc, 1993 : 1369-1396.
6LI L, GORUKANTI S, CHOI Y M,et al. Rapid-onset intranasal delivery of anticonvulsants : pharmacokinetic and pharmacodynamic evaluation in rabbits[J]. Int J Pharm, 2000, 199( 1 ) :65-76.
7CAVALLI R, BARGONI A, CAPUTO O, et al. Transmucosal transport of tobramycin incorporated in solid lipid nanospheres (SLN) after duodenal administration to rats-part I: pharmacokinetics[ J]. Pharmacol Res ,2000 , 42 : 541-545.
8MEHNERT W, MADER K. Solid lipid nanoparticles--production,characterization and applications [ J ]. Adv Drug Deliv Rev, 2001, 47(2-3) :165-196.
9MULLER R H, MADER K, GOHLA S. Solid lipid nanopartieles ( SLN ) for controlled drug delivery--a review of the state of the art [J]. Eur J Pharrn Biopharm,2000,50( 1 ) :161-177.
10ILI,UM L. Transport of drugs from the nasal cavity to the central nervous system[ J]. Eur J Pharm Sci ,2000,11 ( 1 ) : 1-18.
