摘要
目的探讨血常规红细胞参数及网织红细胞参数在轻型β地中海贫血和缺铁性贫血的临床鉴别诊断中的应用价值。方法将98例缺铁性贫血患者设为缺铁贫组,46例轻型β地中海贫血设为地贫组,44例正常体检人员设为对照组。比较3组血常规红细胞参数及网织红细胞参数水平。结果红细胞参数方面,缺铁贫组、地贫组MCV、MCH、MCHC出现降低,与对照组比较有显著差异(P<0.05);缺铁贫组RDW升高,地贫组RDW与对照组比较无显著差异(P>0.05);网织红细胞参数方面,缺铁贫组、地贫组RET#、RET%、IRF、MFR%、HFR%均出现升高,LFR%出现降低,且地贫组变化更为显著;缺铁贫组Ret-He出现降低,与地贫组、对照组比较均有显著差异(P<0.05),而地贫组与对照组比较无显著差异(P>0.05)。结论红细胞及网织红细胞参数在轻型β地中海贫血和缺铁性贫血的临床鉴别诊断中具有重要的意义。
Objective To study the application value of red blood cells and reticulocyte parameters in the clinical identification of light β-mediterranean anemia and iron deficiency anemia. Methods Ninety-eight patients with iron deficiency anemia were set to iron deficiency anemia group, forty-six patients of light β-mediterranean were set to the mediterranean anemia group, and forty-four health subjects were set to the control group. A comparison was made between groups in terms of routine blood red blood cell parameters and the characteristics of reticulocyte parameters. Results Erythrocyte parameters such as MCV, MCH and MCHC in iron deficiency anemia group and Mediterranean anemia group decreased. Compared with the control group, the differences were statistically significant （P 〈 0.05）. RDW in iron deficiency anemia group increased. Compared with the Mediterranean anemia group, the differences in RDW showed no significant difference （P 〉0.05）. As for the reticulocyte parameters, RET#, RET%, IRF, MFR%, HFR% of the iron deficiency anemia group and mediterranean anemia group rose while LFR% reduced. The changes of the mediterranean anemia group were more significant. Ret-He of the iron deficiency group decreased. Compared the Mediterranean anemia group and control group, the differences were statistically different （P 〈 0.05）. But the differences between Mediterranean anemia group and the control group were not statistically significant （P 〉 0.05）. Conclusion Red blood cells parameters and retieulocytes parameters are of important clinical value in diagnosis of β-mediterranean and iron deficiency anemia.
出处
《实用临床医药杂志》
CAS
2013年第15期165-167,共3页
Journal of Clinical Medicine in Practice
关键词
红细胞参数
网织红细胞参数
Β地中海贫血
缺铁性贫血
red blood cell parameters, reticulocyte parameters, β-mediterranean, iron de ficiency anemia
